老挝北部发生重大旋毛虫病疫情，表明当地旋毛虫感染的高流行率。
A major trichinellosis outbreak suggesting a high endemicity of Trichinella infection in northern Laos.
作者信息
Barennes Hubert, Sayasone Somphou, Odermatt Peter, De Bruyne Aymeric, Hongsakhone Sitthivone, Newton Paul N, Vongphrachanh Phengta, Martinez-Aussel Bertrand, Strobel Michel, Dupouy-Camet Jean
机构信息
Institut Francophone pour la Médecine Tropicale, Vientiane Lao PDR.
出版信息
Am J Trop Med Hyg. 2008 Jan;78(1):40-4.
Trichinellosis is an important and under-recognized food-borne zoonosis in Southeast Asia. After 30 years of no reports, a small outbreak was described in Central Lao PDR (Laos) in 2003. Here we report a large outbreak of at least 650 estimated patients in Udomxay (northern Laos) in June 2005. Trichinella ELISA assays on serum from 133 patients and Western blot assays on 16 patients were positive in 67.6% and 81.2%, respectively. No deaths were recorded. Consumption of uncooked or fermented pork at funeral and wedding ceremonies was the main source of infection. Larvae of Trichinella spiralis were found in 1 of 11 local pigs not involved in this outbreak. The results suggest that trichinellosis may be an under-recognized but important endemic disease in Laos and reinforces the need to urgently implement veterinary and educational programs.
旋毛虫病是东南亚一种重要但未得到充分认识的食源性人畜共患病。在30年没有相关报告之后，2003年老挝中部地区（老挝）出现了一次小规模疫情。在此，我们报告2005年6月在乌多姆赛省（老挝北部）发生了一次大规模疫情，估计至少有650名患者。对133名患者血清进行的旋毛虫酶联免疫吸附测定（ELISA）以及对16名患者进行的免疫印迹分析结果显示，阳性率分别为67.6%和81.2%。未记录到死亡病例。在葬礼和婚礼仪式上食用未煮熟或发酵的猪肉是主要感染源。在11头未参与此次疫情的当地猪中，有1头检测出旋毛形线虫幼虫。结果表明，旋毛虫病在老挝可能是一种未得到充分认识但很重要的地方病，这进一步凸显了迫切需要实施兽医和教育项目。
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