Babin E, Sigston E, Hitier M, Dehesdin D, Marie J P, Choussy O
ENT and Head and Neck Surgery Department, CHU-Charles Nicolle University Hospital, 76 000 Rouen, France.
Eur Arch Otorhinolaryngol. 2008 Mar;265(3):265-70. doi: 10.1007/s00405-007-0561-0. Epub 2008 Jan 11.
The principal endpoints in head and neck cancer are survival with improvement of quality of life (QoL) in cancer patients. Patients treated for head and neck cancer suffer from a number of symptom domains: physical symptoms linked to diet and feeding, communication disorders, pain and their general state of health; psychological symptoms including depression, irritability, loss of self-esteem (occasionally feelings of shame), and social symptoms including relationship difficulties with partner (sexual disorders) or with other family members, loss of work, reduction in salary, and sense of uselessness, resulting in a negative impact on their daily life. At present, most tools only partially evaluate patient QoL, concentrating on the global impact of disease and its treatment on patients' physical and psychological condition. The "sociability" of individual patients is rarely evaluated, and the development of qualitative studies in this domain will enable improved understanding of the social factors involved in each patient's adaptability to disease, its treatment and after-effects.
头颈癌的主要终点是癌症患者生存且生活质量（QoL）得到改善。接受头颈癌治疗的患者存在多个症状领域：与饮食和进食相关的身体症状、沟通障碍、疼痛及其总体健康状况；心理症状包括抑郁、易怒、自尊丧失（偶尔有羞耻感），以及社会症状包括与伴侣（性功能障碍）或其他家庭成员的关系困难、失业、薪资减少和无用感，这些都会对他们的日常生活产生负面影响。目前，大多数工具仅部分评估患者的生活质量，侧重于疾病及其治疗对患者身体和心理状况的总体影响。个体患者的“社交能力”很少被评估，该领域定性研究的开展将有助于更好地理解影响每位患者对疾病、其治疗及后遗症适应性的社会因素。
