Division of Spine Surgery, Department Of Orthopaedics, Llandough Hospital, Penarth, UK.
J Orthop Surg Res. 2008 Jan 11;3:3. doi: 10.1186/1749-799X-3-3.
Rapidly destructive arthrosis of the hip is a rare and incompletely understood disorder with scarce literature about variations in natural history within a population.
A series of cases from North Wales with rapid progressive joint destruction and extensive subchondral bone loss in the femoral head and acetabulum are presented. Radiographic findings mimicked those of other disorders such as septic arthritis, rheumatoid and seronegative arthritis, primary osteonecrosis with secondary osteoarthritis, or neuropathic osteoarthropathy, but none of the patients had clinical, pathologic, or laboratory evidence of these entities.
Rapid progression of hip pain and disability was a consistent clinical feature. The average duration of symptoms was 1.4 years. Radiographs obtained at various intervals before surgery (average 14 months) in 18 patients documented rapid hip destruction, involvement being unilateral in 13 cases. All patients underwent total hip arthroplasty, and osteoarthritis was confirmed at pathologic examination.
The authors postulate that these cases represent an uncommon subset of osteoarthritis and regular review, both clinically and radiologically, are required to assess speed of progression and prevent rapid loss of bone stock without the surgeon being aware. These cases are unsuitable for being placed on long waiting list due to technical difficulties in delayed surgery and compromised outcome following surgery.
髋关节快速破坏性关节炎是一种罕见且尚未完全了解的疾病,其在人群中的自然病史变化的相关文献很少。
本文介绍了来自北威尔士的一系列病例,这些病例均存在髋关节进行性快速破坏以及股骨头和髋臼广泛的软骨下骨丢失。影像学表现类似于其他疾病,如化脓性关节炎、类风湿性和血清阴性关节炎、原发性骨坏死继发骨关节炎或神经性骨关节炎,但这些患者均无这些疾病的临床、病理或实验室证据。
髋关节疼痛和功能障碍的快速进展是一个一致的临床特征。平均症状持续时间为 1.4 年。18 例患者在手术前不同时间点(平均 14 个月)拍摄的 X 光片记录了髋关节的快速破坏,其中 13 例为单侧受累。所有患者均接受了全髋关节置换术,病理检查证实为骨关节炎。
作者推测这些病例代表了一种不常见的骨关节炎亚组,需要进行定期的临床和影像学评估,以评估进展速度,并防止在外科医生不知情的情况下迅速丧失骨量。由于延迟手术的技术困难和手术后的结果受损,这些病例不适合放在长等待名单上。