Mehiri-Zghal E, Essalah L, Ghariani A, Mahjoubi W, Reyrolle M, Meugnier H, Forey F, Jarraud S, Freney J, Etienne J, Slim-Saidi L
Laboratoire de microbiologie, hôpital Abderahman-Mami de pneumologie, Ariana, Tunis 2080, Tunisie.
Pathol Biol (Paris). 2008 Jul;56(5):279-82. doi: 10.1016/j.patbio.2007.08.012. Epub 2008 Jan 10.
Legionella pneumophila is a common cause of hospital and community-acquired pneumonia, being transmitted by inhalation of aqueous aerosols. Most outbreaks are linked to contaminated hot water systems and cooling towers. Our study was about the molecular typing of 35 strains of L. pneumophila including four clinical isolates and 31 environmental strains isolated from the distribution systems of 14 hotels. Among the clinical strains, two have the same pattern, however, all were different from the studied environmental strains. For the 31 environmental strains, ten patterns were obtained. Among which, a same pulsotype was found for four strains isolated from four different establishments. In addition, two different pulsotypes were found for strains isolated from the same establishment. The pulsed-field gel electrophoresis showed the existence of various patterns. Although cases of legionellosis were declared in these hotels, there are no epidemiological links between the clinical and environmental strains.
嗜肺军团菌是医院获得性肺炎和社区获得性肺炎的常见病因，通过吸入含水气溶胶传播。大多数疫情暴发与受污染的热水系统和冷却塔有关。我们的研究是关于35株嗜肺军团菌的分子分型，其中包括4株临床分离株和从14家酒店的供水系统中分离出的31株环境菌株。在临床菌株中，有两株具有相同的模式，但所有临床菌株均与所研究的环境菌株不同。对于31株环境菌株，获得了10种模式。其中，从4个不同场所分离出的4株菌株具有相同的脉冲型。此外，从同一场所分离出的菌株发现了两种不同的脉冲型。脉冲场凝胶电泳显示存在多种模式。尽管这些酒店报告了军团病病例，但临床菌株和环境菌株之间没有流行病学联系。
