Luh Shi-ping, Kuo Chih, Tsao Thomas Chang-yao
Department of Surgery, Chia-Yi Christian Hospital and Chung-Shan Medical University and Hospital, Taichung 402, Taiwan, China.
J Zhejiang Univ Sci B. 2008 Jan;9(1):39-43. doi: 10.1631/jzus.B072258.
Breast metastases from extramammary neoplasms are very rare. We presented a 66 year-old female with metastasis of small cell lung carcinoma to the breast. She presented with consolidation over the left upper lobe of her lung undetermined after endobronchial or video-assisted thoracoscopic surgery (VATS) biopsy, and this was treated effectively after antibiotic therapy at initial stage. The left breast lumps were noted 4 months later, and she underwent a modified radical mastectomy under the impression of primary breast carcinoma. However, the subsequent chest imaging revealed re-growing mass over the left mediastinum and hilum, and cells with the same morphological and staining features were found from specimens of transbronchial brushing and biopsy. An accurate diagnosis to distinguish a primary breast carcinoma from metastatic one is very important because the therapeutic planning and the outcome between them are different.
乳腺外肿瘤的乳腺转移非常罕见。我们报告了一位66岁女性,患有小细胞肺癌乳腺转移。她最初因肺左上叶实变在支气管镜或电视辅助胸腔镜手术(VATS)活检后未明确病因,初期经抗生素治疗后得到有效治疗。4个月后发现左乳肿块,她在疑似原发性乳腺癌的情况下接受了改良根治性乳房切除术。然而,随后的胸部影像学检查显示左纵隔和肺门有肿物复现,经支气管刷检和活检标本中发现了具有相同形态和染色特征的细胞。准确诊断原发性乳腺癌与转移性乳腺癌非常重要,因为两者的治疗方案和预后不同。