Hsu Wayne, Sheen-Chen Shyr-Ming, Wang Jui-Long, Huang Chao-Cheng, Ko Sheung-Fat
Department of Surgery, Chang Gung Memorial Hospital, Kaohsiung Medical Center College of Medicine, Chang Gung University, Kaohsiung, Taiwan, ROC.
Anticancer Res. 2008 Mar-Apr;28(2B):1299-301.
Secondary malignancy metastatic to the breast is uncommon with an incidence of 0.5% to 3% of patients with extramammary malignancy. Here, an intriguing, rare case with metastasis to the breast from squamous cell lung carcinoma is reported. A 48-year-old women suffered from chronic cough with sputum for two months. The histological diagnosis, a achieved by bionchoscopic biopsy was squamous cell lung carcinoma. Concurrent chemoradiation therapy was given. Unfortunately, a left breast lump was noted eight months later and metastatic squamous cell lung carcinoma to the breast was diagnosed by surgical biopsy. Secondary malignancy metastatic to the breast is uncommon, yet this entity does exist. In view of the therapeutic implication, a metastatic breast lesion should not be mistaken for a primary breast carcinoma. Only with the awareness of such a possibility can prompt diagnosis and optimal treatment be achieved.
乳腺继发性恶性肿瘤转移并不常见，在乳腺外恶性肿瘤患者中的发生率为0.5%至3%。本文报告了一例罕见且引人关注的病例，为肺鳞状细胞癌转移至乳腺。一名48岁女性，慢性咳嗽伴咳痰两个月。经支气管镜活检获得的组织学诊断为肺鳞状细胞癌。给予同步放化疗。不幸的是，八个月后发现左侧乳腺肿块，经手术活检诊断为肺鳞状细胞癌转移至乳腺。乳腺继发性恶性肿瘤转移并不常见，但确实存在。鉴于其治疗意义，转移性乳腺病变不应被误诊为原发性乳腺癌。只有意识到这种可能性，才能实现及时诊断和最佳治疗。
