Bannon Mark, Marak Creticus, Ashraf Adrita, Smith Chelsea, Nunley Matthew, Guddati Achuta Kumar, Kaushik Prashant
Department of Internal Medicine, House Staff, Northeastern Health System, Tahlequah, OK, USA.
Department of Medicine, Pulmonary and Critical Care, Northeastern Health System, Tahlequah, OK, USA.
Respir Med Case Rep. 2022 Jun 27;38:101693. doi: 10.1016/j.rmcr.2022.101693. eCollection 2022.
Small cell lung cancer (SCLC) is a smoker's disease and occurs almost exclusively in smokers. SCLC is a high-grade neuroendocrine tumor and commonly presents as a central tumor with bulky mediastinal adenopathy. It is notorious for causing widespread disease and paraneoplastic syndromes. The usual sites of metastasis include the liver, brain, bone, and adrenals. SCLC presenting with breast metastasis is unusual; however, there are reports of unilateral and bilateral breast metastases. SCLC with bilateral breast metastases is extremely rare, with only five previously reported cases available in the literature. We are taking this opportunity to report and add to the growing literature on the unusual presentation of a small cell lung cancer with bilateral breast metastases.
小细胞肺癌(SCLC)是一种与吸烟相关的疾病,几乎仅发生于吸烟者。SCLC是一种高级别神经内分泌肿瘤,通常表现为中央型肿瘤并伴有肿大的纵隔淋巴结。它因导致广泛的疾病和副肿瘤综合征而声名狼藉。常见的转移部位包括肝脏、脑、骨和肾上腺。出现乳腺转移的SCLC并不常见;然而,有单侧和双侧乳腺转移的报道。双侧乳腺转移的SCLC极为罕见,文献中仅有5例先前报道的病例。我们借此机会报告并补充关于双侧乳腺转移的小细胞肺癌这种不寻常表现的文献。