Giugliano Dario, Esposito Katherine
Department of Geriatrics and Metabolic Diseases, Division of Metabolic Diseases, University of Naples SUN, Naples, Italy.
Curr Opin Lipidol. 2008 Feb;19(1):63-8. doi: 10.1097/MOL.0b013e3282f2fa4d.
The objective of this article is to present evidence illustrating the relationship between Mediterranean diets and metabolic diseases, including obesity, type 2 diabetes, and the metabolic syndrome, and to briefly discuss potential mechanisms by which these diets can help in disease prevention and treatment.
Although the Mediterranean diet has long been celebrated for its impact on cardiovascular health, mounting evidence indicates a favorable effect on obesity and type 2 diabetes, as well. While health promotion strategies aimed at preventing adult obesity are emphasizing components of Mediterranean dietary patterns, a role for Mediterranean diets in attenuating the inflammatory burden associated with type 2 diabetes is also emerging. Moreover, a lower prevalence of the metabolic syndrome is associated with dietary patterns rich in fruits, vegetables, whole grains, dairy products, and unsaturated fats. Both epidemiological and interventional studies have revealed a protective effect of the Mediterranean diet against mild chronic inflammation and its metabolic complications.
Mounting evidence suggests that Mediterranean diets could serve as an anti-inflammatory dietary pattern, which could help fighting diseases that are related to chronic inflammation, including visceral obesity, type 2 diabetes and the metabolic syndrome.
本文旨在展示相关证据,阐明地中海饮食与代谢性疾病(包括肥胖症、2型糖尿病和代谢综合征)之间的关系,并简要探讨这些饮食有助于疾病预防和治疗的潜在机制。
尽管长期以来地中海饮食对心血管健康的影响备受赞誉,但越来越多的证据表明它对肥胖症和2型糖尿病也有有益影响。虽然旨在预防成人肥胖的健康促进策略强调地中海饮食模式的组成部分,但地中海饮食在减轻与2型糖尿病相关的炎症负担方面的作用也正在显现。此外,代谢综合征患病率较低与富含水果、蔬菜、全谷物、乳制品和不饱和脂肪的饮食模式有关。流行病学研究和干预性研究均显示,地中海饮食对轻度慢性炎症及其代谢并发症具有保护作用。
越来越多的证据表明,地中海饮食可作为一种抗炎饮食模式,有助于对抗与慢性炎症相关的疾病,包括内脏肥胖、2型糖尿病和代谢综合征。