Curtis Luke T, Patel Kalpana
J Altern Complement Med. 2008 Jan-Feb;14(1):79-85. doi: 10.1089/acm.2007.0610.
The purpose of this study was to concisely review the available literature of nutritional and environmental factors on autistic spectrum and attention deficit hyperactivity disorder (ADHD).
Review of journal articles found on the PubMed database and from information from several conference proceedings.
Many, but not all, studies link exposure to toxins such as mercury, lead, pesticides, and in utero smoking exposure to higher levels of autism and/or ADHD. Some studies have reported many nutritional deficiencies in autism/ADHD patients. Numerous studies have reported that supplemental nutrients such as omega-3 fatty acids, vitamins, zinc, magnesium, and phytochemicals may provide moderate benefits to autism/ADHD patients. Avoidance of food allergens, food chemicals, and chelation therapy may also provide some relief to autism/ADHD patients.
Autistic spectrum disorders and ADHD are complicated conditions in which nutritional and environmental factors play major roles. Larger studies are needed to determine optimum multifactorial treatment plans involving nutrition, environmental control,medication, and behavioral/education/speech/physical therapies.
本研究旨在简要回顾关于营养和环境因素对自闭症谱系障碍及注意力缺陷多动障碍(ADHD)影响的现有文献。
检索PubMed数据库中的期刊文章以及若干会议论文集信息进行综述。
许多(但并非全部)研究表明,接触汞、铅、农药等毒素以及孕期吸烟与较高的自闭症和/或ADHD发病率相关。一些研究报告称自闭症/ADHD患者存在多种营养缺乏情况。大量研究表明,补充ω-3脂肪酸、维生素、锌、镁和植物化学物质等营养成分可能对自闭症/ADHD患者有一定益处。避免食物过敏原、食品添加剂以及螯合疗法也可能使自闭症/ADHD患者得到一定缓解。
自闭症谱系障碍和ADHD是复杂病症,营养和环境因素在其中起主要作用。需要开展更大规模的研究以确定涉及营养、环境控制、药物治疗以及行为/教育/言语/物理治疗的最佳多因素治疗方案。