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完成酒精使用障碍识别测试问卷对自我报告的危险饮酒影响的随机对照试验。

Randomized controlled trial of the effects of completing the Alcohol Use Disorders Identification Test questionnaire on self-reported hazardous drinking.

作者信息

McCambridge Jim, Day Maria

机构信息

Centre for Research on Drugs and Health Behaviour, Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.

出版信息

Addiction. 2008 Feb;103(2):241-8. doi: 10.1111/j.1360-0443.2007.02080.x.

DOI:10.1111/j.1360-0443.2007.02080.x
PMID:18199302
Abstract

AIMS

The direct effects of screening on drinking behaviour have not previously been evaluated experimentally. We tested whether screening reduces self-reported hazardous drinking in comparison with a non-screened control group.

DESIGN

Two-arm randomized controlled trial (RCT), with both groups blinded to the true nature of the study.

SETTING AND PARTICIPANTS

A total of 421 university students aged 18-24 years, recruited in five London student unions.

INTERVENTIONS

Both groups completed a brief pen-and-paper general health and socio-demographic questionnaire, which for the experimental group also included the 10-item Alcohol Use Disorders Identification Test (AUDIT) screening questionnaire.

MEASUREMENTS

The primary outcome was the between-group difference in AUDIT score at 2-3-month follow-up. Eight secondary outcomes comprised other aspects of hazardous drinking, including dedicated measures of alcohol consumption, problems and dependence.

FINDINGS

A statistically significant effect size of 0.23 (0.01-0.45) was detected on the designated primary outcome. The marginal nature of the statistical significance of this effect was apparent in additional analyses with covariates. Statistically significant differences were also obtained in three of eight secondary outcomes, and the observed effect sizes were not dissimilar to the known effects of brief interventions.

CONCLUSIONS

It is unclear to what extent these findings represent the effects of screening alone, a Hawthorne effect in which drinking behaviour has changed in response to monitoring, or whether they indicate reporting bias. These possibilities have important implications both for the dissemination of screening as an intervention in its own right and for behavioural intervention trials methodology.

摘要

目的

此前尚未通过实验评估筛查对饮酒行为的直接影响。我们测试了与未进行筛查的对照组相比,筛查是否能减少自我报告的危险饮酒行为。

设计

双臂随机对照试验(RCT),两组均对研究的真实性质不知情。

设置与参与者

在伦敦五个学生会招募了总共421名年龄在18 - 24岁的大学生。

干预措施

两组都完成了一份简短的纸笔式一般健康和社会人口统计学问卷,实验组的问卷还包括10项酒精使用障碍识别测试(AUDIT)筛查问卷。

测量指标

主要结局是在2 - 3个月随访时两组之间AUDIT评分的差异。八个次要结局包括危险饮酒的其他方面,包括专门的饮酒量、问题和依赖程度测量。

研究结果

在指定的主要结局上检测到统计学上显著的效应大小为0.23(0.01 - 0.45)。在对协变量进行的额外分析中,这种效应的统计学显著性的边际性质很明显。在八个次要结局中的三个也获得了统计学上显著的差异,观察到的效应大小与简短干预的已知效应没有差异。

结论

尚不清楚这些发现多大程度上代表了单纯筛查的效果、因监测而导致饮酒行为改变的霍桑效应,或者它们是否表明存在报告偏倚。这些可能性对于将筛查作为一种独立干预措施的推广以及行为干预试验方法学都具有重要意义。

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