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解读功能磁共振成像数据:图谱、模块与维度

Interpreting fMRI data: maps, modules and dimensions.

作者信息

Op de Beeck Hans P, Haushofer Johannes, Kanwisher Nancy G

机构信息

Laboratory of Experimental Psychology, Katholieke Universiteit Leuven, Leuven, Belgium.

出版信息

Nat Rev Neurosci. 2008 Feb;9(2):123-35. doi: 10.1038/nrn2314.

DOI:10.1038/nrn2314
PMID:18200027
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2731480/
Abstract

Neuroimaging research over the past decade has revealed a detailed picture of the functional organization of the human brain. Here we focus on two fundamental questions that are raised by the detailed mapping of sensory and cognitive functions and illustrate these questions with findings from the object-vision pathway. First, are functionally specific regions that are located close together best understood as distinct cortical modules or as parts of a larger-scale cortical map? Second, what functional properties define each cortical map or module? We propose a model in which overlapping continuous maps of simple features give rise to discrete modules that are selective for complex stimuli.

摘要

过去十年的神经影像学研究揭示了人类大脑功能组织的详细图景。在此,我们聚焦于由感觉和认知功能的详细映射所引发的两个基本问题,并用来自物体视觉通路的研究结果来说明这些问题。第一,紧密相邻的功能特异性区域,是最好理解为不同的皮质模块,还是更大规模皮质图谱的一部分?第二,哪些功能特性定义了每个皮质图谱或模块?我们提出了一个模型,其中简单特征的重叠连续图谱产生了对复杂刺激具有选择性的离散模块。

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