Silva Antonio Rafael da, Portela Edson Gustavo Lima, Matos Wilma Batista de, Silva Camila Cristina Bastos, Gonçalves Eloisa da Graça do Rosario
Centro de Referência em Doenças Infecciosas e Parasitárias, Departamento de Patologia, Universidade Federal do Maranhão, São Luis, MA.
Rev Soc Bras Med Trop. 2007 Nov-Dec;40(6):657-60. doi: 10.1590/s0037-86822007000600012.
This study had the aim of determining the coefficient of leprosy detection among the student population of the municipality of Buriticupu, State of Maranhão. An active case search method was used, covering a population of 14,653 students, in 53 schools within the municipal network. Clinical examination gave rise to a leprosy diagnosis for 20 students, which represents a detection coefficient of 13.6/10,000 students. Cutaneous lymph bacilloscopy was performed on all cases, and it was positive in two samples. The predominant clinical form was the indeterminate form, with 12 cases (60%), followed by the tuberculoid form, with five (25%) and the dimorphous form with two (10%). Biopsies were then taken from the lesions of 11 patients, and histopathological analysis showed common findings of hyperkeratosis, mononuclear inflammatory infiltrate and ectasia of vessels and isolated arrector pili muscles. The study also enabled identification of some other infectious skin diseases: pityriasis versicolor in 793, scabies in 361 and dermatophytosis in 119. A variety of nonspecific conditions were also detected, such as scars, nevi and excoriation, in 1,020 students.
本研究旨在确定马拉尼昂州布里蒂库普市学生群体中的麻风病检出系数。采用主动病例搜索方法，覆盖市立学校网络中的53所学校，共14,653名学生。临床检查诊断出20名学生患有麻风病，检出系数为13.6/10,000名学生。对所有病例均进行了皮肤淋巴组织涂片镜检，其中两份样本呈阳性。主要临床类型为未定类，有12例（60%），其次为结核样型，有5例（25%），双型有2例（10%）。随后对11例患者的皮损进行活检，组织病理学分析显示常见表现为角化过度、单核细胞炎性浸润、血管扩张以及立毛肌孤立。该研究还发现了一些其他感染性皮肤病：花斑癣793例、疥疮361例和皮肤癣菌病119例。在1,020名学生中还检测到各种非特异性情况，如瘢痕、痣和擦伤。
