Rizzardi G, Marulli G, Bortolotti L, Calabrese F, Sartori F, Rea F
Division of Thoracic Surgery, Cardiologic, Thoracic and Vascular Sciences, University of Padova, Padova, Italy.
Thorac Cardiovasc Surg. 2008 Feb;56(1):42-5. doi: 10.1055/s-2007-965741.
Typical carcinoids are low grade malignant neuroendocrine neoplasms, mostly located centrally in the tracheobronchial tree. The aim of our study was to analyse the long-term survival and surgical treatment outcome in patients submitted to parenchyma-sparing resections for typical central carcinoid tumours.
We retrospectively reviewed the data of 70 patients who underwent sleeve resections or bronchoplastic procedures. We performed 21 sleeve lobectomies, 9 sleeve resections of the main bronchus, 25 bronchoplasties associated with lung resections and 15 isolated wedge bronchoplasties. Nine patients (12.8%) had nodal metastases.
There was no operative mortality; postoperative complications occurred in one patient (1.4%) who presented an empyema. At long-term follow-up evaluation, we were able to report good results: all patients were alive and nobody manifested recurrence; one patient had a late cicatricial bronchial stenosis, which was treated with laser therapy.
This series of central typical bronchial carcinoids, treated with sleeve or bronchoplastic resection, demonstrated an excellent outcome. Our results suggest that, in experienced and skilled hands, conservative procedures must be considered the treatment of choice for the management of these tumours.
典型类癌是低度恶性神经内分泌肿瘤，大多位于气管支气管树的中央部位。我们研究的目的是分析接受保留实质组织切除术治疗的典型中央型类癌患者的长期生存率及手术治疗效果。
我们回顾性分析了70例行袖状切除术或支气管成形术患者的数据。我们实施了21例袖状肺叶切除术、9例主支气管袖状切除术、25例与肺切除术相关的支气管成形术以及15例单纯楔形支气管成形术。9例患者（12.8%）有淋巴结转移。
无手术死亡；1例患者（1.4%）发生脓胸这一术后并发症。在长期随访评估中，我们能够报告良好的结果：所有患者均存活，无人出现复发；1例患者发生晚期瘢痕性支气管狭窄，经激光治疗。
这一系列接受袖状或支气管成形切除术治疗的中央型典型支气管类癌显示出极佳的治疗效果。我们的结果表明，在经验丰富和技术熟练的医生手中，保守手术应被视为这些肿瘤治疗的首选方法。
