Meiwes J, Müller W, Grabley S, Schudok M
Hoechst AG, Frankfurt am Main.
Biomed Biochim Acta. 1991;50(10-11):S80-3.
The arginine-specific protease Clostripain could efficiently be produced following improved fermentation and isolation procedures. Preparative scale kinetically controlled peptide synthesis of -Arg-Pro- and Arg-Xaa- containing peptides could successfully be performed in high yields with free and immobilized enzyme preparations.
通过改进发酵和分离程序，可以高效生产精氨酸特异性蛋白酶梭菌蛋白酶。使用游离酶制剂和固定化酶制剂，能够以高产率成功进行动力学控制的制备规模的含-Arg-Pro-和Arg-Xaa-肽的肽合成。
