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儿童炎症性肠病的特殊问题

Special issues in pediatric inflammatory bowel disease.

作者信息

Dubinsky Marla

机构信息

Pediatric IBD Center, Cedars-Sinai Medical Center, David Geffen School of Medicine, University of California-Los Angeles, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.

出版信息

World J Gastroenterol. 2008 Jan 21;14(3):413-20. doi: 10.3748/wjg.14.413.

DOI:10.3748/wjg.14.413
PMID:18200664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2679130/
Abstract

The incidence of pediatric inflammatory bowel disease (IBD) is rising and recent advances in diagnostics and therapeutics have improved the care provided to these children. There are distinguishing features worth noting between early onset and adult onset IBD. Physical and psychosocial development remains a critical target for the comprehensive management of pediatric IBD. Children are not just little adults and consideration must be given to the stages of development and how these stages impact disease presentation and management. The final stage will be the transition from pediatric care to that of adult oriented care and special consideration must be given to make this a successful process. This review highlights special considerations in the management of the child with IBD.

摘要

儿童炎症性肠病(IBD)的发病率正在上升,诊断和治疗方面的最新进展改善了为这些儿童提供的护理。早发型和成人型IBD之间存在一些值得注意的区别特征。身体和心理社会发育仍然是儿童IBD综合管理的关键目标。儿童并非只是小成年人,必须考虑发育阶段以及这些阶段如何影响疾病表现和管理。最后阶段将是从儿科护理向成人导向护理的过渡,必须给予特别考虑以使这一过程成功。本综述强调了IBD患儿管理中的特殊考虑因素。

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本文引用的文献

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Both preoperative perinuclear antineutrophil cytoplasmic antibody and anti-CBir1 expression in ulcerative colitis patients influence pouchitis development after ileal pouch-anal anastomosis.溃疡性结肠炎患者术前的核周抗中性粒细胞胞浆抗体及抗CBir1表达均会影响回肠储袋肛管吻合术后储袋炎的发生。
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Serum immune responses predict rapid disease progression among children with Crohn's disease: immune responses predict disease progression.血清免疫反应可预测克罗恩病患儿的疾病快速进展:免疫反应可预测疾病进展。
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