Tallon B, Lamb S
Department of Dermatology, Auckland District Health Board, New Zealand.
Clin Exp Dermatol. 2008 May;33(3):276-7. doi: 10.1111/j.1365-2230.2007.02633.x. Epub 2008 Jan 14.
Docetaxel is a commonly used taxane in chemotherapy treatment. A reported 70% of infusions are associated with skin reactions. We report a case of flagellate erythema after treatment with docetaxel. Although flagellate erythema has been reported previously with bleomycin and peplomycin, to our knowledge this is the first description of flagellate erythema induced by docetaxel, and should be added to the list of causes of this skin reaction. Oral corticosteroid treatment may prevent its appearance.
多西他赛是化疗治疗中常用的紫杉烷类药物。据报道,70%的输注会伴有皮肤反应。我们报告一例多西他赛治疗后出现的鞭毛虫样红斑病例。尽管先前已有使用博来霉素和培洛霉素后出现鞭毛虫样红斑的报道,但据我们所知,这是多西他赛诱发鞭毛虫样红斑的首次描述,应将其添加到这种皮肤反应的病因列表中。口服皮质类固醇治疗可能会预防其出现。