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博来霉素诱发的鞭毛虫样皮炎:再探讨

Bleomycin-Induced Flagellate Dermatitis: Revisited.

作者信息

Verma Pallavi, Rajaram Shalini, Heda Ayush, Sundriyal Deepak, Tiwari Parmita, Sahoo Ipshita, Panta Shilpa, Bordoloi Mriganka, Bhan Himani, Sharma Dipendra

机构信息

Obstetrics and Gynaecology (Gynaecologic Oncology), All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

Medical Oncology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

出版信息

Cureus. 2022 Sep 16;14(9):e29221. doi: 10.7759/cureus.29221. eCollection 2022 Sep.

Abstract

Flagellate dermatitis caused by bleomycin is a rare side effect with a distinctive pattern of whip-like, linear streaks. The clinical presentation has become uncommon nowadays as bleomycin use in conventional chemotherapy regimens has decreased. We present a case of a 30-year-old female diagnosed with ovarian germ cell tumour, managed with bleomycin, etoposide, and cisplatin (BEP) and later developed a widespread rash indicative of classic flagellate dermatitis. This brief report emphasizes the significance of detection and management of this transient dermatological complication in patients receiving bleomycin.

摘要

博来霉素引起的鞭毛虫样皮炎是一种罕见的副作用,具有独特的鞭状线性条纹图案。如今,随着博来霉素在传统化疗方案中的使用减少,其临床表现已不常见。我们报告一例30岁女性,被诊断为卵巢生殖细胞肿瘤,接受博来霉素、依托泊苷和顺铂(BEP)治疗,后来出现了广泛的皮疹,提示典型的鞭毛虫样皮炎。本简要报告强调了在接受博来霉素治疗的患者中检测和处理这种短暂性皮肤并发症的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ed/9571210/640fc862f739/cureus-0014-00000029221-i01.jpg

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