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欧迪欧软鼻(Odiosoft-Rhino)在评估鼻阻塞方面的疗效:一项针对常年性变应性鼻炎患者使用布地奈德鼻喷雾剂治疗后与鼻声反射测量法的对比研究。

Efficacy of Odiosoft-Rhino in assessment of nasal obstruction: a comparative study with acoustic rhinometry after treatment with budesonide nasal spray in patients with perennial allergic rhinitis.

作者信息

Tahamiler Rauf, Yener Murat, Canakcioglu Salih

机构信息

Department of Otorhinolaryngology, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.

出版信息

Am J Rhinol. 2007 Nov-Dec;21(6):711-5. doi: 10.2500/ajr.2007.21.3106.

DOI:10.2500/ajr.2007.21.3106
PMID:18201452
Abstract

BACKGROUND

Odiosoft-Rhino (OR) is new software and equipment that can be used to measure changes in nasal obstruction after intranasal steroid treatment. OR is a promising method for measuring the degree of nasal obstruction. OR can precisely analyze nasal sound spectra in decibels, which is generated by nasal airflow. We studied the reliability of OR for assessing declining nasal obstruction after budesonide nasal spray treatment.

METHODS

Sixty-five patients with perennial allergic rhinitis (PAR) were enrolled in the study, and 52 of these patients completed the study. Nasal endoscopic examination, acoustic rhinometry (AR), and OR were performed and symptom scores were compared before and after 3 months of treatment with intranasal budesonide. All of the patients received 7 days of placebo treatment before receiving budesonide.

RESULTS

There was a significant difference in the visual analog scores of nasal obstruction and in the examination scores before and after the treatment for both the right and the left nasal cavities. Pretreatment AR findings and OR findings in the 2000- to 4000-Hz and 4000- to 6000-Hz intervals for both sides were significantly different from the posttreatment measurements (p = 0.000). Both AR and OR can assess the efficacy of budesonide nasal spray treatment for nasal obstruction in patients with PAR.

CONCLUSION

Both AR and OR are effective for assessing nasal obstruction and monitoring treatment efficacy but, as a simple and noninvasive test, OR can be used with confidence.

摘要

背景

Odiosoft-Rhino(OR)是一种可用于测量鼻内类固醇治疗后鼻阻塞变化的新型软件和设备。OR是一种很有前景的测量鼻阻塞程度的方法。OR能够精确分析由鼻气流产生的以分贝为单位的鼻声谱。我们研究了OR在评估布地奈德鼻喷雾剂治疗后鼻阻塞减轻情况方面的可靠性。

方法

65例常年性变应性鼻炎(PAR)患者纳入本研究,其中52例完成研究。在鼻内使用布地奈德治疗3个月前后进行鼻内镜检查、鼻声反射(AR)和OR检查,并比较症状评分。所有患者在接受布地奈德治疗前均接受了7天的安慰剂治疗。

结果

左右鼻腔治疗前后的鼻阻塞视觉模拟评分和检查评分均有显著差异。两侧2000至4000赫兹和4000至6000赫兹区间的治疗前AR结果和OR结果与治疗后测量值有显著差异(p = 0.000)。AR和OR均可评估布地奈德鼻喷雾剂治疗PAR患者鼻阻塞的疗效。

结论

AR和OR在评估鼻阻塞和监测治疗效果方面均有效,但作为一种简单且无创的检查,OR可放心使用。

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Efficacy of Odiosoft-Rhino in assessment of nasal obstruction: a comparative study with acoustic rhinometry after treatment with budesonide nasal spray in patients with perennial allergic rhinitis.欧迪欧软鼻(Odiosoft-Rhino)在评估鼻阻塞方面的疗效:一项针对常年性变应性鼻炎患者使用布地奈德鼻喷雾剂治疗后与鼻声反射测量法的对比研究。
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