Srirangam Shalom J, Darling Richard, Stopford Maureen, Neilson Donald
Department of Urology, Blackburn Royal Infirmary, Blackburn, UK.
Ann R Coll Surg Engl. 2008 Jan;90(1):40-4. doi: 10.1308/003588408X242240.
Most series of percutaneous nephrolithotomy (PCNL) from single specialised centres represent optimum results achievable and may not reflect outcomes of everyday practice. We analysed the practice in our region.
Medical records of 178 patients undergoing PCNL in 2002 in 12 participating hospital trusts were retrospectively analysed.
Even outside the tertiary referral centres, there was a 6-fold difference between trusts in the frequency of PCNL. In 28% of cases, another stone-removing modality had been tried first. Failed renal puncture was a major cause of abandoning surgery (9%). An indication of the difficulty in obtaining complete stone clearance is that only 107 (60%) operation notes recorded complete clearance, while 75 (42%) patients required a subsequent procedure (13% a secondary PCNL). Use of supra 12th rib punctures was small (6%) as was the rate of 'tube-less' PCNL (4%). Some 22% had simultaneous ureteric stent insertion. Approximately 8% of cases required a blood transfusion. Thirty-eight patients (23%) had a proven infection (UTI) pre-operatively (> 10(4) organisms; > 10 white blood cells) with almost all patients receiving antibiotics at anaesthesia induction. Postoperative sepsis rates (temperature > 38.5 degrees C) were similar in those with and without a pre-operative UTI (18.4% versus 14.3%) and pre-operative antibiotics appeared to have little extra protective effect. Severe sepsis was rare with no patient requiring intensive care admission for this reason. Median length of stay postoperatively was 5 days.
These results present important figures to quote when counselling patients pre-operatively, albeit that the degree of difficulty (and hence the likelihood of problems) is identifiable from stone and anatomical configurations. In addition, the present data are a more accurate reflection of urinary stone surgery in non-tertiary, general urological practice.
大多数来自单一专科中心的经皮肾镜取石术(PCNL)系列报道代表了所能达到的最佳结果,可能无法反映日常实践的结果。我们分析了我们地区的实际情况。
回顾性分析了2002年在12家参与的医院信托机构中接受PCNL的178例患者的病历。
即使在三级转诊中心之外,各信托机构在PCNL频率上也存在6倍的差异。在28%的病例中,首先尝试了另一种结石清除方式。肾穿刺失败是放弃手术的主要原因(9%)。难以实现结石完全清除的一个迹象是,只有107份(60%)手术记录记载了结石完全清除,而75例(42%)患者需要后续手术(13%进行二次PCNL)。第12肋以上穿刺的使用比例很小(6%),“无管”PCNL的比例也很低(4%)。约22%的患者同时插入输尿管支架。约8%的病例需要输血。38例患者(23%)术前证实有感染(UTI)(细菌>10⁴;白细胞>10),几乎所有患者在麻醉诱导时都接受了抗生素治疗。术前有UTI和无UTI患者的术后脓毒症发生率(体温>38.5℃)相似(18.4%对14.3%),术前使用抗生素似乎没有额外的保护作用。严重脓毒症很少见,没有患者因此需要入住重症监护病房。术后中位住院时间为5天。
这些结果提供了术前向患者咨询时可引用的重要数据,尽管从结石和解剖结构可以确定困难程度(以及出现问题的可能性)。此外,目前的数据更准确地反映了非三级普通泌尿外科实践中的尿路结石手术情况。