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撤回:白藜芦醇在小鼠皮肤肿瘤发生过程中通过线粒体途径诱导细胞凋亡。

RETRACTED: Resveratrol induces apoptosis involving mitochondrial pathways in mouse skin tumorigenesis.

作者信息

Kalra Neetu, Roy Preeti, Prasad Sahdeo, Shukla Yogeshwer

机构信息

Proteomics Laboratory, Industrial Toxicology Research Centre, P.O. Box 80, M.G. Marg, Lucknow-226001, India.

出版信息

Life Sci. 2008 Feb 13;82(7-8):348-58. doi: 10.1016/j.lfs.2007.11.006. Epub 2007 Nov 28.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. Multiple figures in this article appear to be falsified/fabricated, and can not be verified as the corresponding author does not have the original data. Figure 2. It appears that data has been duplicated in panels V and VI. Figure 3A. Lanes II and VI in the p53 wild band appear to be duplicated. Figure 4A. Lanes I, II, V and VI of the Beta-actin blot appear to be the same data replicated. Figure 4B. The representative blots in the Bcl-2 band, lanes V and VI are identical, as are all lanes in the Beta-actin band. Figure 5B. Lanes III and IV of the Apaf 1 band, when rotated and vertically stretched, are duplicated and appear in Figure 3D as lanes III and IV of the Cytochrome C blot in “Chemopreventive potential of resveratrol in mouse skin tumors through regulation of mitochondrial and PI3K/AKT signaling pathways.” Pharmaceutical Research (2009). Doi: 10.1007/s11095-008-9723-z. Figure 5C. Lanes II and V of the Caspase 9 band appear to be duplicated. Figure 5E. The bands in lane V and VI of the Beta-actin blot are duplicated. Figure 5B and 5C. The Beta-actin lane IV band in 5B and lane IV in 5C appear to be duplicated from Figure 6B in “Hepatoprotective effects of lupeol and mango pulp extract of carcinogen induced alteration in Swiss albino mice.” Molecular Nutrition & Food Research (2007). Doi: 10.1002/mnfr.200600113.

摘要

本文已被撤回

请参阅爱思唯尔关于文章撤回的政策(https://www.elsevier.com/about/our-business/policies/article-withdrawal)。本文应主编要求被撤回。本文中的多个图似乎是伪造/编造的,由于通讯作者没有原始数据,无法进行核实。图2。图版V和VI中的数据似乎被重复使用。图3A。p53野生型条带中的泳道II和VI似乎被重复使用。图4A。β-肌动蛋白印迹中的泳道I、II、V和VI似乎是相同数据的重复。图4B。Bcl-2条带中泳道V和VI的代表性印迹相同,β-肌动蛋白条带中的所有泳道也相同。图5B。Apaf 1条带的泳道III和IV在旋转并垂直拉伸后被重复使用,并出现在《白藜芦醇通过调节线粒体和PI3K/AKT信号通路对小鼠皮肤肿瘤的化学预防潜力》(《药物研究》,2009年。doi:10.1007/s11095-008-9723-z)中图3D的细胞色素C印迹的泳道III和IV中。图5C。半胱天冬酶9条带的泳道II和V似乎被重复使用。图5E。β-肌动蛋白印迹中泳道V和VI中的条带被重复使用。图5B和5C。图5B中β-肌动蛋白泳道IV条带和图5C中的泳道IV似乎是从《羽扇豆醇和芒果果肉提取物对致癌物诱导的瑞士白化小鼠改变的肝保护作用》(《分子营养与食品研究》,2007年。doi:10.1002/mnfr.200600113)中图6B重复而来。

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