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撤回:茶多酚通过诱导细胞凋亡增强宫颈癌顺铂化疗敏感性。

RETRACTED: Tea polyphenols enhance cisplatin chemosensitivity in cervical cancer cells via induction of apoptosis.

机构信息

Proteomics Laboratory, Council of Scientific & Industrial Research, (Indian Institute of Toxicology Research), P.O. Box 80, M.G. Marg, Lucknow-226001, India.

Proteomics Laboratory, Council of Scientific & Industrial Research, (Indian Institute of Toxicology Research), P.O. Box 80, M.G. Marg, Lucknow-226001, India.

出版信息

Life Sci. 2013 Jul 19;93(1):7-16. doi: 10.1016/j.lfs.2013.02.001. Epub 2013 Feb 9.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. Multiple figures in this article appear to be falsified/fabricated. Figure 2A and C. The representative dot plots from the EGCG (15ug/ml)+CDDP (10ug/ml) and TF (15ug/ml) groups appear to be duplicated. Figures 3, 4 and 6. Multiple Western blot bands appear to be rotated and reused throughout Figure 3 (A and B); 4 (A and B) and 6 (A, B, C). In particular, the Cytochrome-c blot in Figure 3B is duplicated and flipped in Figure 6B as p-NFKB. The p53 blot in Figure 3B is duplicated in Figure 6C as p-NFKB. The B-actin blot in Figure 3B is shown as an unmarked control lane (flipped in Figure 6B. The p53 band in Figure 3C is very similar to the Caspase 9 blot in Figure 4B and is cropped and duplicated in Figure 6A as p-NFKB by cisplatin in SiHa cells. The Caspase 3 blot in Figure 4A is rotated and flipped and appears in Figure 6B as p-IKBa.

摘要

本文已被撤回

请参阅爱思唯尔关于文章撤回的政策(https://www.elsevier.com/about/our-business/policies/article-withdrawal)。应主编要求,撤回本文。本文中的多个图像似乎是伪造/捏造的。图 2A 和 C. EGCG(15μg/ml)+CDDP(10μg/ml)和 TF(15μg/ml)组的代表性点图似乎是重复的。图 3、4 和 6. 多个 Western blot 条带似乎在整个图 3(A 和 B);4(A 和 B)和 6(A、B、C)中旋转和重复使用。特别是,图 3B 中的细胞色素 c 印迹在图 6B 中作为 p-NFKB 被复制和翻转。图 3B 中的 p53 印迹在图 6C 中作为 p-NFKB 被复制。图 3B 中的 B-肌动蛋白印迹显示为未标记的对照泳道(在图 6B 中翻转。图 3C 中的 p53 条带与图 4B 中的 Caspase 9 条带非常相似,并用顺铂在 SiHa 细胞中作为 p-NFKB 在图 6A 中被切割和复制。图 4A 中的 Caspase 3 印迹被旋转和翻转,并在图 6B 中作为 p-IKBa 出现。

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