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医疗补助计划覆盖的变应性鼻炎儿童的变应性免疫治疗:治疗模式、资源利用及成本

Allergy immunotherapy among Medicaid-enrolled children with allergic rhinitis: patterns of care, resource use, and costs.

作者信息

Hankin Cheryl S, Cox Linda, Lang David, Levin Arthur, Gross Gary, Eavy Gene, Meltzer Eli, Burgoyne Doug, Bronstone Amy, Wang Zhaohui

机构信息

BioMedEcon, LLC, PO Box 129, Moss Beach, CA 94038, USA.

出版信息

J Allergy Clin Immunol. 2008 Jan;121(1):227-32. doi: 10.1016/j.jaci.2007.10.026.

DOI:10.1016/j.jaci.2007.10.026
PMID:18206509
Abstract

BACKGROUND

Although research demonstrates that allergy immunotherapy (IT) improves allergic rhinitis (AR) outcomes, little is known about IT patterns of care and associated resource use and costs among US children with diagnoses of AR.

OBJECTIVE

We sought to examine characteristics associated with receiving IT, patterns of IT care, and health care use and costs incurred in the 6 months before versus after IT.

METHODS

We performed retrospective Florida Medicaid claims data (1997-2004) analysis of children (<18 years of age) given new diagnoses of AR.

RESULTS

Of 102,390 patients with new diagnoses of AR, 3048 (3.0%) received IT. Male patients, Hispanic patients, and those with concomitant asthma were significantly more likely to receive IT. Approximately 53% completed less than 1 year and 84% completed less than 3 years of IT. Patients who received IT used significantly less pharmacy (12.1 vs 8.9 claims, P < .0001), outpatient (30.7 vs 22.9 visits, P < .0001), and inpatient (1.2 vs 0.4 admissions, P = .02) resources in the 6 months after versus before IT. Pharmacy ($330 vs $60, P < .0001), outpatient ($735 vs $270, P < .0001), and inpatient ($2441 vs $1, P < .0001) costs (including costs for IT care) were significantly reduced after IT.

CONCLUSION

Despite suboptimal treatment persistence (only 16% of patients completed 3 years of IT), resource use and costs after treatment were significantly reduced from pre-IT levels.

摘要

背景

尽管研究表明过敏免疫疗法(IT)可改善过敏性鼻炎(AR)的治疗效果,但对于美国诊断为AR的儿童,IT的护理模式以及相关资源使用和成本情况却知之甚少。

目的

我们试图研究与接受IT相关的特征、IT护理模式以及IT前后6个月内的医疗保健使用情况和成本。

方法

我们对佛罗里达州医疗补助索赔数据(1997 - 2004年)进行了回顾性分析,对象为新诊断为AR的儿童(<18岁)。

结果

在102,390例新诊断为AR的患者中,3048例(3.0%)接受了IT治疗。男性患者、西班牙裔患者以及伴有哮喘的患者接受IT治疗的可能性显著更高。约53%的患者完成IT治疗的时间不足1年,84%的患者不足3年。接受IT治疗的患者在IT治疗后6个月内使用的药房资源(12.1次与8.9次索赔,P <.0001)、门诊资源(30.7次与22.9次就诊,P <.0001)和住院资源(1.2次与0.4次入院,P =.02)明显少于治疗前。IT治疗后,药房成本(330美元与60美元,P <.0001)、门诊成本(735美元与270美元,P <.0001)和住院成本(2441美元与1美元,P <.0001)(包括IT护理成本)显著降低。

结论

尽管治疗持续性欠佳(仅16%的患者完成了3年的IT治疗),但治疗后的资源使用和成本较IT治疗前水平显著降低。

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