Parent X, Sovalat H, Beck-Wirth G, Jung G, Henon P
Service d'Hématologie et des Maladies du Sang, Hôpital du Hasenrain, Mulhouse, France.
Nouv Rev Fr Hematol (1978). 1991;33(4):303-6.
We report a case of acute non lymphoblastic leukemia in which clinical and cytological patterns corresponded closely to the M3 variant as defined in the FAB classification, although we did not find the characteristic t (15; 17) chromosomal translocation. However, cytochemistry, DNA content studies and immunophenotyping showed unusual patterns suggesting a monocytic differentiation of most of the blast cells, while a smaller population of blasts showed in contrast typical markers of granulocytic lineage.
我们报告了一例急性非淋巴细胞白血病病例，其临床和细胞学模式与FAB分类中定义的M3变异型密切相符，尽管我们未发现特征性的t(15;17)染色体易位。然而，细胞化学、DNA含量研究和免疫表型分析显示出不寻常的模式，提示大多数原始细胞向单核细胞分化，而一小部分原始细胞则呈现出粒细胞系的典型标志物。
