Fallatah A, Tarakji M, Amuesi J
Department of Urology, King Fahd Hospital, Jeddah, Saudi Arabia.
Saudi J Kidney Dis Transpl. 2001 Oct-Dec;12(4):520-4.
We herewith report 10 patients with xanthogranulomatous pyelonephritis (XGP) who were treated in our department between the years 1988 and 2000. The patients' age ranged from 20 to 60 years (mean 45 years); there were seven males and three females giving a male-female ratio of 2.3:1. Sixty percent of the patients were over 50 years old. The lesion was unilateral in all cases and pyonephrosis was found in seven patients. Nine cases had associated renal stones (90%), which led to non-functioning kidney in all these cases. Two cases had associated fistulae (one uretero-colonic fistula and one reno-cutaneous fistula). One case of focal XGP was found to be associated with renal cell carcinoma while a second patient with diffuse obstructive type of XGP and renal stone had associated transitional cell carcinoma of the renal pelvis. In all patients, the urine culture was negative. Pus culture revealed Escherechia coli in four cases (40%), Salmonella Para B in one, and no organism could be grown in four other cases. One case did not have any pus. All patients were treated with nephrectomy.
我们在此报告1988年至2000年间在我科接受治疗的10例黄色肉芽肿性肾盂肾炎(XGP)患者。患者年龄在20至60岁之间(平均45岁);男性7例,女性3例,男女比例为2.3:1。60%的患者年龄超过50岁。所有病例病变均为单侧,7例患者伴有肾积脓。9例患者伴有肾结石(90%),所有这些病例中肾脏均无功能。2例患者伴有瘘管(1例输尿管结肠瘘和1例肾皮肤瘘)。1例局灶性XGP患者被发现与肾细胞癌相关,而另1例弥漫性梗阻型XGP并伴有肾结石的患者伴有肾盂移行细胞癌。所有患者尿培养均为阴性。脓液培养4例(40%)检出大肠杆菌,1例检出副伤寒沙门氏菌,另外4例未培养出细菌。1例患者无脓液。所有患者均接受了肾切除术。