Rösler M, Retz W, Retz-Junginger P, Stieglitz R D, Kessler H, Reimherr F, Wender P H
Neurozentrum, Universitätsklinikum des Saarlandes, 66421, Homburg/Saar.
Nervenarzt. 2008 Mar;79(3):320-7. doi: 10.1007/s00115-007-2375-0.
We report on a study comparing different systems for the diagnosis of attention deficit hyperactivity disorder (ADHD) in adulthood. Recruited for evaluation were 168 patients referred to our ADHD outpatient unit. We used the Diagnostic and Statistical Manual of Mental Disorders 4th edn. (DSM-IV), International Classification of Diseases 10th edn. (ICD-10), and Utah criteria for diagnostic assessment and the Wender Utah rating scale, ADHD Self Report (ADHD-SR), and Wender Reimherr Adult Attention Deficit Disorder Rating Scale as psychopathological assessment tools. We present basic psychometric data of the Wender-Reimherr Interview (WRI). Internal consistency was determined as 0.82 (alpha). The inter-rater reliability was 1.0 (kappa coefficient) regarding ADHD diagnoses, and the ICC was 0.98 referring to the WRI total scores. The convergent validity with the ADHD-SR was 0.65 (Spearman coefficient). In 126 of 168 patients an ADHD diagnosis was made according to at least one of the three systems. The DSM-IV diagnostic set led to 119 ADHD diagnoses. As compared with the two other systems, this is about the minimum level for an ADHD diagnosis. All of the 87 ADHD diagnoses according to ICD-10 were covered by DSM-IV. The ICD-10 had no independent psychopathological items and therefore offered no additional points for the diagnostic procedure than the DSM-IV. The situation regarding Utah criteria is different. These criteria contain seven psychopathological domains: inattention, hyperactivity, disorganisation, impulsivity, affective lability, overreactivity, and hot temper. They can be assessed by use of the WRI. Ninety-three of 168 patients were diagnosed as having ADHD according to the Utah concept, which is much lower than with the DSM-IV. The particular definition of the disorder by the Utah criteria resulted in seven patients having only a Utah diagnosis but no DSM-IV diagnosis. Thus we are in a position to say that the Utah criteria have a relatively high level for making an ADHD diagnosis but in certain cases move beyond the DSM-IV. Of the patients 56% had ADHD diagnoses according to all three classification instruments. Examining the factor structure of the ADHD psychopathology represented by seven WRI and three ADHD-SR subscales, we found a two-factor solution explaining for 63% of the variance. Factor 1 was designated by impulsivity, affective lability, hyperactivity, and hot temper; factor 2 consisted of inattention, disorganisation, and overreactivity.
我们报告了一项关于比较不同系统用于诊断成人注意力缺陷多动障碍(ADHD)的研究。招募了168名被转介到我们ADHD门诊的患者进行评估。我们使用《精神疾病诊断与统计手册》第4版(DSM-IV)、《国际疾病分类》第10版(ICD-10)以及犹他州诊断标准进行诊断评估,并使用温德犹他评定量表、ADHD自我报告(ADHD-SR)和温德-赖姆赫尔成人注意力缺陷障碍评定量表作为心理病理学评估工具。我们展示了温德-赖姆赫尔访谈(WRI)的基本心理测量数据。内部一致性确定为0.82(α)。关于ADHD诊断,评定者间信度为1.0(kappa系数),而关于WRI总分,组内相关系数(ICC)为0.98。与ADHD-SR的收敛效度为0.65(斯皮尔曼系数)。在168名患者中,有126名患者根据三种系统中的至少一种被诊断为ADHD。DSM-IV诊断集得出119例ADHD诊断。与其他两种系统相比,这大约是ADHD诊断的最低水平。根据ICD-10做出的所有87例ADHD诊断都被DSM-IV涵盖。ICD-10没有独立的心理病理学条目,因此在诊断过程中比DSM-IV没有提供更多分数。犹他州标准的情况则不同。这些标准包含七个心理病理学领域:注意力不集中、多动、杂乱无章、冲动、情感不稳定、反应过度和脾气暴躁。它们可以通过WRI进行评估。根据犹他州概念,168名患者中有93名被诊断为患有ADHD,这比DSM-IV诊断的要低得多。犹他州标准对该障碍的特定定义导致7名患者仅有犹他州诊断但没有DSM-IV诊断。因此我们可以说,犹他州标准做出ADHD诊断的水平相对较高,但在某些情况下超出了DSM-IV。56%的患者根据所有三种分类工具都被诊断为患有ADHD。检查由七个WRI和三个ADHD-SR子量表所代表的ADHD心理病理学的因子结构,我们发现一个双因子解决方案解释了63%的方差。因子1由冲动、情感不稳定、多动和脾气暴躁组成;因子2由注意力不集中、杂乱无章和反应过度组成。