Mourtzinos I, Kalogeropoulos N, Papadakis S E, Konstantinou K, Karathanos V T
Laboratory of Food Chemistry, Biochemistry and Physical Chemistry, Department of Nutrition & Dietetics, Harokopio University, 70 El. Venizelou Ave., Kallithea, 176 71, Athens, Greece.
J Food Sci. 2008 Jan;73(1):S89-94. doi: 10.1111/j.1750-3841.2007.00609.x.
The encapsulation of thymol and geraniol in beta-cyclodextrin (beta-CD) and modified starch (MS) by spray- and freeze-drying was studied. The formation of thymol/beta-CD and geraniol/beta-CD inclusion complexes was confirmed by differential scanning calorimetry (DSC). Oxidative DSC revealed that the monoterpenes enclosed in the beta-CD cavity were protected against oxidation, remaining intact in temperatures at which free monoterpenes were oxidized. Phase solubility studies showed that the inclusion complexes of thymol and geraniol with beta-CD are more soluble in water than the free molecules themselves. Furthermore, in order to evaluate the fraction of monoterpenes that can be released from their complexes with MS in aqueous media, a series of release experiments were conducted.
研究了通过喷雾干燥和冷冻干燥将百里香酚和香叶醇包封在β-环糊精（β-CD）和变性淀粉（MS）中的情况。通过差示扫描量热法（DSC）证实了百里香酚/β-CD和香叶醇/β-CD包合物的形成。氧化DSC表明，包封在β-CD腔内的单萜类化合物受到氧化保护，在游离单萜类化合物被氧化的温度下保持完整。相溶解度研究表明，百里香酚和香叶醇与β-CD的包合物在水中比游离分子本身更易溶解。此外，为了评估单萜类化合物在水性介质中从其与MS的复合物中释放的比例，进行了一系列释放实验。
