Department of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, Korea.
J Microencapsul. 2010;27(6):496-505. doi: 10.3109/02652041003681398.
The study investigated the thermo-physical properties of eugenol encapsulated with beta-cyclodextrin (beta-CD) by molecular inclusion and eugenol release characteristics at various relative humidities and storage temperatures. Particle size, Zeta-potential, thermal transition and morphology of beta-CD-Eugenol complex after freeze-drying measured using Nanosizer, differential scanning calorimeter (DSC) and transmission electron microscopy (TEM), respectively. The particle size, Zeta-potential and inclusion efficiency of encapsulated eugenol presented approximately 340 nm, -34.5 mV and 91.7% after freeze-drying, respectively. The relationship between retention rate of eugenol and time during release was described by a mathematical model of Avrami equation. In these events, the parameter of release mechanism and the release rate constant were rapidly elevated with increasing relative humidity and storage temperature. Furthermore, the Arrhenius activation energy for the release of eugenol decreases with increasing relative humidity and storage temperature.
该研究通过分子包合考察了β-环糊精（β-CD）包封丁香酚的热物理性质以及在不同相对湿度和储存温度下丁香酚的释放特性。使用纳米粒度仪、差示扫描量热仪（DSC）和透射电子显微镜（TEM）分别测量了冷冻干燥后β-CD-丁香酚复合物的粒径、Zeta 电位、热转变和形态。包封丁香酚的粒径、Zeta 电位和包封效率分别约为 340nm、-34.5mV 和 91.7%。通过 Avrami 方程的数学模型描述了释放过程中丁香酚保留率与时间之间的关系。在这些事件中，随着相对湿度和储存温度的升高，释放机制的参数和释放速率常数迅速升高。此外，随着相对湿度和储存温度的升高，丁香酚释放的阿累尼乌斯活化能降低。
