Cheng Yan, Dong Yi-Yang, Dong Mei-Xian, Wang Chao, Su Ning, Sun Yuan-Tao, Liu Juan, Zheng Hong-Yan, Schrader Andreas, Rohr Mathias, Liu Wei
Beijing Sino-German Union Cosmetic Institute Co, Chinese Academy of Inspection and Quarantine, Beijing, China.
Skin Res Technol. 2008 Feb;14(1):45-52. doi: 10.1111/j.1600-0846.2007.00260.x.
BACKGROUND/PURPOSE: The efficacy of cosmetics on human skin measured under normal mild laboratory environment might be discounted by exterior environment factors such as wind, UV exposure, etc. Few studies have focused on the 'genuine' efficacy of cosmetics on human skin during exposure to external rigorous environment. The aim of this study was to develop a model for the evaluation of the efficacy of cosmetics on human skin under simulated rigorous environment.
We measured skin water content and transepidermal water loss (TEWL) before and after products application under simulated windy and sub-erythema UV exposure treatment in a constant temperature and humidity laboratory.
The results showed that the products had higher water content and lower TEWL at 2, 4 and 8 h of products application, and ameliorated the skin moisturization situation after a 3-week continuous use of the products. In addition, the products might protect the skin to maintain the normal water content and TEWL under the simulated windy or sub-erythema UV exposure treatment in our laboratory when compared with untreated area.
Our data indicate that this model may provide a more accurate evaluation for the genuine moisturizing effect of cosmetics under external natural climate.
背景/目的：在正常温和的实验室环境下测量的化妆品对人体皮肤的功效，可能会受到风、紫外线照射等外部环境因素的影响而大打折扣。很少有研究关注化妆品在暴露于外部恶劣环境期间对人体皮肤的“真正”功效。本研究的目的是建立一个在模拟恶劣环境下评估化妆品对人体皮肤功效的模型。
在恒温恒湿实验室中，我们在模拟有风及亚红斑紫外线照射处理的情况下，测量了产品涂抹前后的皮肤含水量和经表皮水分流失（TEWL）。
结果显示，在产品涂抹2小时、4小时和8小时时，产品具有较高的含水量和较低的TEWL，并且在连续使用产品3周后改善了皮肤保湿状况。此外，与未处理区域相比，在我们实验室模拟有风或亚红斑紫外线照射处理的情况下，产品可能会保护皮肤维持正常的含水量和TEWL。
我们的数据表明，该模型可能为外部自然气候下化妆品的真正保湿效果提供更准确的评估。
