Larson David W, Davies Michael M, Dozois Eric J, Cima Robert R, Piotrowicz Karen, Anderson Kari, Barnes Sunni A, Harmsen W Scott, Young-Fadok Tonia M, Wolff Bruce G, Pemberton John H
Division of Colon and Rectal Surgery, Mayo Clinic Rochester, Rochester, MN 55905, USA.
Dis Colon Rectum. 2008 Apr;51(4):392-6. doi: 10.1007/s10350-007-9180-5. Epub 2008 Jan 24.
This study was designed to compare self-reported sexual function, body image, and quality of life outcomes among ulcerative colitis patients undergoing laparoscopic or open ileal pouch-anal anastomosis.
Between 1978 and 2004, 100 laparoscopic and 189 open operations were performed in patients who were identified from a previously published cohort. Patients were surveyed one year after operation to evaluate sexual function, body image, and quality of life.
A total of 125 of 289 patients (43 percent) returned completed surveys. There were no significant differences in terms of demographics, complications, or long-term functional outcomes between those who completed the surveys and those who did not. There were no clinical differences in results between laparoscopic and open patients using the three survey instruments. Orgasmic function scores were lower in men who underwent laparoscopic ileal pouch-anal anastomosis (P < 0.05) compared with open ileal pouch-anal anastomosis. Overall, sexual function scores were equal to or better than normal values for men but were lower in women. Finally, overall body image and quality of life scores were above the means published for the United States.
After ileal pouch-anal anastomosis, men and women reported excellent body image and high cosmetic and quality of life scores regardless of operative approach. Female sexual function was more adversely affected after ileal pouch-anal anastomosis than was male sexual function.
本研究旨在比较接受腹腔镜或开放回肠储袋肛管吻合术的溃疡性结肠炎患者自我报告的性功能、身体形象和生活质量结果。
1978年至2004年间，对先前发表的队列研究中确定的患者进行了100例腹腔镜手术和189例开放手术。术后一年对患者进行调查，以评估性功能、身体形象和生活质量。
289例患者中有125例（43%）返回了完整的调查问卷。完成调查的患者与未完成调查的患者在人口统计学、并发症或长期功能结果方面没有显著差异。使用三种调查问卷工具，腹腔镜手术患者和开放手术患者的结果在临床上没有差异。与开放回肠储袋肛管吻合术相比，接受腹腔镜回肠储袋肛管吻合术的男性性高潮功能评分较低（P<0.05）。总体而言，男性的性功能评分等于或优于正常值，但女性的性功能评分较低。最后，总体身体形象和生活质量评分高于美国公布的平均值。
回肠储袋肛管吻合术后，无论手术方式如何，男性和女性均报告身体形象良好，美容和生活质量评分较高。回肠储袋肛管吻合术后，女性性功能比男性性功能受到的负面影响更大。
