Davies R Justin, O'Connor Brenda I, Victor Charles, MacRae Helen M, Cohen Zane, McLeod Robin S
Department of Surgery, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada.
Dis Colon Rectum. 2008 Jul;51(7):1032-5. doi: 10.1007/s10350-008-9248-x. Epub 2008 May 3.
This study was designed to assess the effect of ileal pouch-anal anastomosis on sexual function and quality of life in men and women.
Sexual function of patients undergoing ileal pouch-anal anastomosis from February 2005 to June 2006 was prospectively evaluated using the International Index of Erectile Function in men and Female Sexual Function Index in women. Quality of life was assessed using the Short Inflammatory Bowel Disease Questionnaire. Preoperative scores were compared with scores at 6 and 12 months postoperatively.
Of 110 patients eligible for inclusion, 59 (53.6 percent) agreed to participate. Male sexual function and erectile function scores remained high 12 months after surgery (mean International Index of Erectile Function score 51.7 preoperative vs. 58.3 at 12 months postoperative; P = not significant (NS)). Abnormal sexual function decreased from 33.3 percent before surgery to 22.7 percent 12 months after surgery (P = NS). Female sexual function improved 12 months after surgery (mean Female Sexual Function Index score 19.2 preoperative vs. 27 at 12 months postoperative; P = 0.031). Abnormal sexual function decreased from 73.1 percent before surgery to 25 percent 12 months after surgery (P = 0.001). Quality of life significantly improved after ileal pouch-anal anastomosis in both sexes.
In men, ileal pouch-anal anastomosis does not have an adverse effect on sexual function, whereas sexual function in women seems to improve 12 months after surgery.
本研究旨在评估回肠储袋肛管吻合术对男性和女性性功能及生活质量的影响。
对2005年2月至2006年6月期间接受回肠储袋肛管吻合术的患者,采用男性国际勃起功能指数和女性性功能指数对其性功能进行前瞻性评估。使用简短炎症性肠病问卷评估生活质量。将术前评分与术后6个月和12个月的评分进行比较。
在110名符合纳入标准的患者中,59名(53.6%)同意参与。术后12个月男性性功能和勃起功能评分仍保持较高水平(平均国际勃起功能指数评分术前为51.7,术后12个月为58.3;P =无显著性差异(NS))。性功能异常从术前的33.3%降至术后12个月的22.7%(P = NS)。女性性功能在术后12个月有所改善(平均女性性功能指数评分术前为19.2,术后12个月为27;P = 0.031)。性功能异常从术前的73.1%降至术后12个月的25%(P = 0.001)。回肠储袋肛管吻合术后男女生活质量均显著改善。
对男性而言,回肠储袋肛管吻合术对性功能无不良影响,而女性性功能在术后12个月似乎有所改善。