Li Zhen, Tan Bien, Allix Mathieu, Cooper Andrew I, Rosseinsky Matthew J
Department of Chemistry, University of Liverpool, L69 7ZD, UK.
Small. 2008 Feb;4(2):231-9. doi: 10.1002/smll.200700575.
Water-soluble monodisperse superparamagnetic Fe3O4 nanocrystals decorated with two distinct functional groups are prepared in a single-step procedure by injecting iron precursors into a refluxing aqueous solution of a polymer ligand, trithiol-terminated poly(methacrylic acid) (PMAA-PTTM), bearing both carboxylate and thiol functionalities. The ratio of carboxylic acid groups in the polymer-protecting ligand to the iron precursors plays a key role in determining the particle size and particle size distribution. The surface functionalities of the ligands allow post-synthesis modification of the materials to produce water-soluble fluorescent magnetic nanocrystals.
通过将铁前驱体注入到具有羧酸盐和硫醇官能团的聚合物配体——三硫醇封端的聚（甲基丙烯酸）（PMAA-PTTM）的回流水溶液中，采用一步法制备了装饰有两种不同官能团的水溶性单分散超顺磁性Fe3O4纳米晶体。聚合物保护配体中的羧酸基团与铁前驱体的比例在决定粒径和粒径分布方面起着关键作用。配体的表面官能团允许对材料进行合成后修饰，以制备水溶性荧光磁性纳米晶体。
