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卵巢有丝分裂活跃的细胞性纤维瘤:一例报告。

Mitotically active cellular fibroma of the ovary: A case report.

作者信息

Yıldırım Nuri, Saatli Bahadır, Akalın Fatma, Ulukuş Çağnur, Obuz Funda, Saygılı Uğur

机构信息

Dokuz Eylül University Faculty of Medicine, Department of Obstetrics and Gynecology, İzmir, Turkey.

Dokuz Eylül University Faculty of Medicine, Department of Pathology, İzmir, Turkey.

出版信息

Turk J Obstet Gynecol. 2015 Mar;12(1):53-55. doi: 10.4274/tjod.11298. Epub 2015 Mar 15.

DOI:10.4274/tjod.11298
PMID:28913042
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5558406/
Abstract

Fibromas are classified in a spectrum from fibromas to fibrosarcomas according to the number of mitosis they include. Malignant fibrosarcomas which have aggressive pattern show higher mitotic activity and nuclear atypia. Cellular fibromas with less than 4 mitotic figures under 10 high power fields (HPF) are benign. "Mitotically active cellular fibromas" that are classified between the cellular fibromas and fibrosarcomas, have ≥4 mitotic figures in 10 HPF but do not have nuclear atypia. A very few cases of mitotically active cellular fibromas have been reported in the literature. In this report, we present the case of mitotically active cellular fibroma in a patient who applied to our clinic with the complaint of pelvic mass.

摘要

纤维瘤根据其所含有丝分裂数在从纤维瘤到纤维肉瘤的范围内进行分类。具有侵袭性模式的恶性纤维肉瘤表现出更高的有丝分裂活性和核异型性。在10个高倍视野(HPF)下有丝分裂数少于4个的细胞性纤维瘤是良性的。介于细胞性纤维瘤和纤维肉瘤之间的“有丝分裂活跃的细胞性纤维瘤”,在10个HPF中有≥4个有丝分裂数,但没有核异型性。文献中报道的有丝分裂活跃的细胞性纤维瘤病例非常少。在本报告中,我们介绍了一名因盆腔肿块主诉前来我院就诊的患者患有有丝分裂活跃的细胞性纤维瘤的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/5558406/dfc623a2ebee/TJOD-12-53-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/5558406/4e7529971051/TJOD-12-53-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/5558406/dfc623a2ebee/TJOD-12-53-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/5558406/4e7529971051/TJOD-12-53-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b967/5558406/dfc623a2ebee/TJOD-12-53-g2.jpg

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本文引用的文献

1
Mitotically active cellular fibroma of the ovary: a case report and a review of the literature.卵巢有丝分裂活跃的细胞性纤维瘤:一例报告并文献复习
Eur J Gynaecol Oncol. 2014;35(1):81-3.
2
[Mitotically active cellular fibroma of ovary: a clinicopathologic analysis].[卵巢有丝分裂活跃的细胞性纤维瘤:临床病理分析]
Zhonghua Bing Li Xue Za Zhi. 2013 Oct;42(10):660-4.
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Recurrence of mitotically active cellular fibroma of the ovary.卵巢有丝分裂活跃性细胞纤维瘤复发
Obstet Gynecol Int. 2009;2009:803062. doi: 10.1155/2009/803062. Epub 2009 Jan 12.
4
A unique fibrous tumor of the ovary: fibrosarcoma or mitotically active cellular fibroma?一种独特的卵巢纤维性肿瘤:纤维肉瘤还是有丝分裂活跃的细胞性纤维瘤?
Anticancer Res. 2007 Nov-Dec;27(6C):4365-9.
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Cellular fibromas of the ovary: a study of 75 cases including 40 mitotically active tumors emphasizing their distinction from fibrosarcoma.卵巢细胞性纤维瘤:一项包含75例病例的研究,其中40例为有丝分裂活跃肿瘤,着重强调其与纤维肉瘤的鉴别。
Am J Surg Pathol. 2006 Aug;30(8):929-38. doi: 10.1097/00000478-200608000-00001.
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Ovarian fibrosarcoma with five-year survival: a case report.
Eur J Gynaecol Oncol. 2002;23(4):345-6.
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Ovarian fibrosarcoma with long-term survival: a case report.卵巢纤维肉瘤伴长期生存:一例报告
Int J Gynecol Cancer. 2001 Jul-Aug;11(4):331-3. doi: 10.1046/j.1525-1438.2001.011004331.x.
8
Cellular fibromas and fibrosarcomas of the ovary: a comparative clinicopathologic analysis of seventeen cases.卵巢的细胞性纤维瘤和纤维肉瘤:17例病例的比较临床病理分析
Cancer. 1981 Jun 1;47(11):2663-70. doi: 10.1002/1097-0142(19810601)47:11<2663::aid-cncr2820471124>3.0.co;2-v.
9
Cellular fibroma masquerading as ovarian carcinoma.伪装成卵巢癌的细胞性纤维瘤。
Obstet Gynecol. 1990 Sep;76(3 Pt 2):530-1.