Yıldırım Nuri, Saatli Bahadır, Akalın Fatma, Ulukuş Çağnur, Obuz Funda, Saygılı Uğur
Dokuz Eylül University Faculty of Medicine, Department of Obstetrics and Gynecology, İzmir, Turkey.
Dokuz Eylül University Faculty of Medicine, Department of Pathology, İzmir, Turkey.
Turk J Obstet Gynecol. 2015 Mar;12(1):53-55. doi: 10.4274/tjod.11298. Epub 2015 Mar 15.
Fibromas are classified in a spectrum from fibromas to fibrosarcomas according to the number of mitosis they include. Malignant fibrosarcomas which have aggressive pattern show higher mitotic activity and nuclear atypia. Cellular fibromas with less than 4 mitotic figures under 10 high power fields (HPF) are benign. "Mitotically active cellular fibromas" that are classified between the cellular fibromas and fibrosarcomas, have ≥4 mitotic figures in 10 HPF but do not have nuclear atypia. A very few cases of mitotically active cellular fibromas have been reported in the literature. In this report, we present the case of mitotically active cellular fibroma in a patient who applied to our clinic with the complaint of pelvic mass.
纤维瘤根据其所含有丝分裂数在从纤维瘤到纤维肉瘤的范围内进行分类。具有侵袭性模式的恶性纤维肉瘤表现出更高的有丝分裂活性和核异型性。在10个高倍视野(HPF)下有丝分裂数少于4个的细胞性纤维瘤是良性的。介于细胞性纤维瘤和纤维肉瘤之间的“有丝分裂活跃的细胞性纤维瘤”,在10个HPF中有≥4个有丝分裂数,但没有核异型性。文献中报道的有丝分裂活跃的细胞性纤维瘤病例非常少。在本报告中,我们介绍了一名因盆腔肿块主诉前来我院就诊的患者患有有丝分裂活跃的细胞性纤维瘤的病例。