Inst. of Stat. & Decision Sci., Duke Univ., Durham, NC.
IEEE Trans Med Imaging. 1994;13(3):569-71. doi: 10.1109/42.310891.
The use of the expectation-maximization algorithm to obtain pseudo-maximum likelihood estimates (i.e. the EM-ML algorithm) of radiopharmaceutical distributions based on data collected from emission computed tomography (ECT) systems is now a well developed area, as witnessed by a number of recent articles on that topic, including the detailed study of the relative performance of EM-ML and FBP reconstructions provided in J. Llacer et al. (ibid., vol. 12, p. 215-31, 1993). However, there remains considerable confusion in the field regarding appropriate stopping rules for EM-ML algorithms, and in this correspondence the author attempts to detail a shortcoming of one of the more recent and innovative stopping rule criteria. In particular, the author discusses the effect of total photon counts on stopping criteria based on cross-validation.
利用期望最大化算法(即 EM-ML 算法)从发射型计算机断层(ECT)系统采集的数据中获取放射性药物分布的伪最大似然估计,目前已经是一个发展成熟的领域,从近期发表的一些相关文章,包括 J. Llacer 等人提供的关于 EM-ML 和 FBP 重建相对性能的详细研究(同上,第 12 卷,第 215-31 页,1993 年)中可以看出。然而,在 EM-ML 算法的适当停止规则方面,该领域仍然存在相当大的混淆,在本通信中,作者试图详细说明最近提出的、具有创新性的停止规则标准之一的一个缺陷。具体来说,作者讨论了基于交叉验证的总光子计数对停止规则的影响。