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腹膜种植转移对复发性结直肠癌伴肠梗阻的临床意义

[A clinical significance of peritoneal carcinomatosis to recurrent colorectal cancer with ileus].

作者信息

Kato Takeshi, Miyake Yasuhiro, Doi Takashi, Oshima Kazuteru, Handa Rio, Hoshi Minako, Makari Yoichi, Oshima Satoshi, Iijima Shouhei, Kurokawa Eiji, Kikkawa Nobuteru

机构信息

Dept. of Surgery, Minoh City Hospital Gastrointestinal Research Center.

出版信息

Gan To Kagaku Ryoho. 2007 Nov;34(12):1949-51.

Abstract

We studied a clinical significance of peritoneal carcinomatosis to metastatic recurrent colorectal cancer with ileus. The subjects were 16 patients with ileus confirmed in 1995-2005. Of the 16 patients, 7 had surgical treatment and the other 9 had conservative treatment. The median survival time of the 16 patients was 98 days; the 7 patients of surgical treatment were 235 days; the 9 patients of conservative treatment were only 67 days. Only 4 patients survived more than 200 days. These 4 patients had surgical treatment, and were the cases where no peritoneal fluid was confirmed and the metastatic tumor was excised. However, only 2 patients improved in QOL. The 3 patients in the surgical treatment were aggravated. An optimum resection may prolong a survival time and patient's QOL could be improved. On the other hand, an extended resection may contribute to shorting a survival time.

摘要

我们研究了腹膜癌病对伴有肠梗阻的转移性复发性结直肠癌的临床意义。研究对象为1995年至2005年确诊为肠梗阻的16例患者。这16例患者中,7例接受了手术治疗,另外9例接受了保守治疗。16例患者的中位生存时间为98天;7例接受手术治疗的患者为235天;9例接受保守治疗的患者仅为67天。只有4例患者存活超过200天。这4例患者接受了手术治疗,且为未确认有腹腔积液且切除了转移瘤的病例。然而,只有2例患者的生活质量得到改善。手术治疗的3例患者病情加重。最佳切除术可能会延长生存时间,且患者的生活质量可以得到改善。另一方面,扩大切除术可能会导致生存时间缩短。

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