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失眠的药物治疗。

Pharmacotherapy of insomnia.

作者信息

Bhat Abid, Shafi Fariha, El Solh Ali A

机构信息

University of Missouri at Kansas City, Division of Pulmonary and Critical Care Medicine, Geriatrics and Hospital Medicine, Department of Medicine, Truman Medical Center, Hospital Hill, Kansas City, Missouri, USA.

出版信息

Expert Opin Pharmacother. 2008 Feb;9(3):351-62. doi: 10.1517/14656566.9.3.351.

Abstract

Insomnia is the most common sleep disorder in the industrialized world. A variety of precipitating events have been identified, but when it becomes a persistent problem, maladaptive patterns become established, thereby, perpetuating the sleep disturbance. Individuals with insomnia have impaired next-day functioning, which impacts their quality of life and places them at increased risk of motor vehicle accidents. Insomnia is commonly associated with chronic medical conditions, as well as an increased incidence of mental disorders. Despite considerable scientific advances in both the understanding and treatment, insomnia continues to be inadequately identified and treated, with < 15% of those with severe insomnia receiving appropriate treatment. The mainstay of treatment for insomnia is cognitive-behavioral therapy, along with judicious use of hypnotic agents.

摘要

失眠是工业化世界中最常见的睡眠障碍。已经确定了多种引发事件,但当它成为一个持续存在的问题时,就会形成适应不良的模式,从而使睡眠障碍持续存在。失眠患者次日的功能会受损,这会影响他们的生活质量,并使他们发生机动车事故的风险增加。失眠通常与慢性疾病以及精神障碍发病率的增加有关。尽管在理解和治疗方面取得了相当大的科学进展,但失眠仍然没有得到充分的识别和治疗,严重失眠患者中只有不到15%接受了适当的治疗。失眠治疗的主要方法是认知行为疗法,同时谨慎使用催眠药物。

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