Abbott R, Cutting C B, Wisoff J H, Thorne C H, Epstein F J
Department of Neurosurgery, New York University Medical Center, N.Y.
Pediatr Neurosurg. 1991;17(4):182-4. doi: 10.1159/000120592.
Two cases of aplasia cutis congenita with associated bony defects are presented to highlight the dangers of delayed coverage of exposed dura. Management of one case was complicated by repeated local and systemic sepsis and the other by repeated, life-threatening hemorrhage. Early, definitive coverage of these defects using full thickness skin flaps avoids the risks of hemorrhage and should, if the recipient bed is clean, lessen the incidence of complicating sepsis.
本文报告两例先天性皮肤发育不全合并骨缺损的病例，以强调延迟覆盖暴露硬脑膜的危险性。其中一例患者的治疗因反复发生局部和全身感染而变得复杂，另一例则因反复出现危及生命的出血而复杂化。使用全厚皮瓣早期、明确地覆盖这些缺损可避免出血风险，并且如果受区创面清洁，应可降低并发感染的发生率。
