Strauss E G, Strauss J H
Division of Biology, California Institute of Technology, Pasadena 91125.
Curr Opin Genet Dev. 1991 Dec;1(4):485-93. doi: 10.1016/s0959-437x(05)80196-0.
The explosive pace of sequencing of RNA viruses is leading to rapid advances in our understanding of the evolution of these viruses and of the ways in which their genomes are organized and expressed. New insights are coming not only from genomic nucleotide sequence comparisons, but also from direct sequencing of transcribed mRNAs and of RNAs that serve as intermediates in replication.
RNA病毒测序的迅猛发展正促使我们在理解这些病毒的进化以及其基因组的组织和表达方式方面取得快速进展。新的见解不仅来自基因组核苷酸序列比较,还来自转录mRNA以及作为复制中间体的RNA的直接测序。