Ceriello Antonio
Centre of Excellence in Diabetes and Endocrinology, University Hospital of Coventry and Warwickshire, Warwick Medical School, University of Warwick, Coventry, UK.
Diabetes Care. 2008 Feb;31 Suppl 2:S181-4. doi: 10.2337/dc08-s245.
Recently oxidative stress has been proposed as the cause of hypertension. An imbalance in superoxide and nitric oxide production may account for reduced vasodilation, which in turn can favor the development of hypertension. In vitro and in human studies support this hypothesis. The supplementation of antioxidants, particularly in the form of fresh fruit and vegetables, reduces blood pressure, supporting a role for free radicals in hypertension.
最近，氧化应激被认为是高血压的病因。超氧化物和一氧化氮生成失衡可能导致血管舒张功能降低，进而引发高血压。体外实验和人体研究均支持这一假说。补充抗氧化剂，尤其是新鲜水果和蔬菜形式的抗氧化剂，可降低血压，这表明自由基在高血压发病过程中起作用。
