Burns Paul, Sheahan Patrick, Doody Jaime, Kinsella John
Department of Otalaryngology-Head and Neck Surgery, St. James's Hospital, Dublin, Ireland.
Head Neck. 2008 Aug;30(8):1124-7. doi: 10.1002/hed.20762.
We report the 10th case in the English-language literature describing clavicular osteomyelitis that presented after radical treatment for laryngeal carcinoma and discuss the pertinent diagnostic and therapeutic measures. It presented a diagnostic dilemma. The differential diagnosis included tumor recurrence, metastatic bone disease, and postradiotherapy complications.
A 45-year-old man who was a heavy smoker and known drug abuser presented with acute airway compromise and was diagnosed with squamous cell carcinoma involving the glottis and subglottis. Total laryngectomy, total thyroidectomy, and bilateral neck dissection were performed, and the patient underwent chemoradiotherapy. On follow-up 1 year later, the patient was seen with left stomal dehiscence and a large area of cellulitis extending across the left clavicle and down to the axilla. At surgery, a large anterior chest wall abscess was found. Biopsy showed no evidence of tumor. After aggressive treatment, the patient remains disease free.
This condition is rarely encountered after major head and neck surgery. Aggressive surgical debridement and antibiotic therapy remains the mainstay of treatment. Prompt diagnosis and treatment are mandatory due to the potential life-threatening complications associated with the condition. Bony resection will aid in adequate flap placement.
我们报告了英文文献中第10例描述喉癌根治治疗后出现的锁骨骨髓炎的病例,并讨论相关的诊断和治疗措施。该病例呈现出诊断困境。鉴别诊断包括肿瘤复发、骨转移疾病和放疗后并发症。
一名45岁男性,重度吸烟者且有药物滥用史,因急性气道梗阻就诊,被诊断为累及声门和声门下的鳞状细胞癌。患者接受了全喉切除术、全甲状腺切除术和双侧颈部清扫术,并接受了放化疗。1年后随访时,发现患者左侧造口裂开,大面积蜂窝织炎延伸至左锁骨并向下至腋窝。手术时,发现一个巨大的前胸壁脓肿。活检未发现肿瘤证据。经过积极治疗,患者无疾病复发。
这种情况在头颈部大手术后很少见。积极的手术清创和抗生素治疗仍然是主要的治疗方法。由于该疾病可能伴有危及生命的并发症,必须及时诊断和治疗。骨切除有助于合适的皮瓣放置。