Kjems E, Schydlowski P, Søndergaard J O
Department of Surgery, Sundby Hospital, Copenhagen, Denmark.
Rev Med Chir Soc Med Nat Iasi. 1991 Jul-Dec;95(3-4):265-8.
A retrospective study of 325 consecutive patients suffering colorectal adenocarcinoma, allowed in 141, the determination of the influence of blood transfusion upon the risk of recurrence/metastases over a minimum observation period of 6 months. Of 29 patients not receiving blood transfusion, 6 were subjected to recurrence/metastases. Of 112 patients receiving blood transfusion, 45 suffered recurrence/metastases. No significant difference in the risk of developing recurrence/metastases was seen when the primary tumor was Dukes' class A and C. When the primary tumor was Dukes' class B, a significantly higher risk of recurrence/metastases was seen in the group receiving blood transfusion. A constrained use of blood transfusion in connection with colorectal surgery is recommended until definitive immunological studies determined the influence of blood transfusion upon the risk of recurrence/metastases.
对325例连续性结肠直肠癌患者进行回顾性研究，其中141例患者在至少6个月的观察期内确定了输血对复发/转移风险的影响。在29例未接受输血的患者中，6例出现复发/转移。在112例接受输血的患者中，45例出现复发/转移。当原发肿瘤为Dukes A级和C级时，复发/转移风险无显著差异。当原发肿瘤为Dukes B级时，接受输血的组中复发/转移风险显著更高。在明确的免疫学研究确定输血对复发/转移风险的影响之前，建议在结直肠手术中限制输血的使用。
