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玻利维亚出血热疫区的灭鼠计划。

Rodent control programmes in areas affected by Bolivian haemorrhagic fever.

作者信息

Mercado R

出版信息

Bull World Health Organ. 1975;52(4-6):691-6.

PMID:182405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2366668/
Abstract

Bolivian haemorrhagic fever (BHF) caused by Machupo virus is acquired by contact with the excretions and secretions of Calomys callosus, an indigenous cricetine rodent which is preadapted to peridomestic habitats. It competes successfully with Mus musculus, but not with Rattus rattus. A successful disease control programme has functioned in Beni Department since 1964. It is based on trapping surveys and the detection of splenomegaly in Calomys rodents as an index of chronic virus infection. Mass trapping and poisoning are used initially, and regular trapping is employed to control Calomys populations in towns where disease has occurred. More than 1000 cases of BHF were recorded from 1960-1964, but less than 200 in the past 10 years. The cost of this programme is approximately $30 000 annually.

摘要

由马丘波病毒引起的玻利维亚出血热(BHF)是通过接触加氏小鼠(Calomys callosus)的排泄物和分泌物而感染的,加氏小鼠是一种原产于南美洲的仓鼠科啮齿动物,已适应在人类居住地周围的环境中生存。它能成功地与小家鼠竞争,但不能与褐家鼠竞争。自1964年以来,贝尼省实施了一项成功的疾病控制计划。该计划基于诱捕调查,并将加氏小鼠的脾脏肿大作为慢性病毒感染的指标进行检测。最初采用大规模诱捕和投毒的方法,在出现疾病的城镇,定期进行诱捕以控制加氏小鼠的数量。1960年至1964年期间记录了1000多例玻利维亚出血热病例,但在过去10年中不到200例。该计划的成本约为每年3万美元。

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本文引用的文献

1
Immune tolerance in Calomys callosus infected with Machupo virus.感染马丘波病毒的南美稻鼠的免疫耐受
Nature. 1969 Jun 14;222(5198):1090-1. doi: 10.1038/2221090a0.
2
Chronic infection of rodents by Machupo virus.马丘波病毒对啮齿动物的慢性感染。
Science. 1965 Dec 17;150(3703):1618-9. doi: 10.1126/science.150.3703.1618.
3
Hemorrhagic fevers of Southeast Asia and South America: a comparative appraisal.东南亚和南美洲的出血热:比较评估
Prog Med Virol. 1967;9:105-58.