登革2型病毒在澳大利亚托雷斯海峡的埃及伊蚊、白纹伊蚊和盾纹伊蚊中的感染与传播

Infection and dissemination of dengue virus type 2 in Aedes aegypti, Aedes albopictus, and Aedes scutellaris from the Torres Strait, Australia.

作者信息

Moore Peter R, Johnson Petrina H, Smith Greg A, Ritchie Scott A, Van Den Hurk Andrew F

机构信息

Department of Microbiology and Parasitology, School of Molecular and Microbial Sciences, The University of Queensland, St. Lucia, Queensland 4072, Australia.

出版信息

J Am Mosq Control Assoc. 2007 Dec;23(4):383-8. doi: 10.2987/5598.1.

DOI:10.2987/5598.1

PMID:18240514

Abstract

To determine their relative roles in transmission of dengue virus (DENV) in the Torres Strait region of northern Australia, we examined infection and dissemination of a sympatric strain of dengue virus type 2 (DENV-2) in Aedes scutellaris, Ae. albopictus, and Ae. aegypti. In experiments using membrane feeders for virus exposure, infection rates were 83% and 43% for Ae. scutellaris and Ae. aegypti, respectively. Salivary gland infection rates for both species were 43%. In experiments using pledgets for virus exposure, infection rates for Ae. aegypti, Ae. scutellaris, and Ae. albopictus were 68%, 55%, and 37%, respectively. Aedes albopictus exhibited the greatest barriers to infection with only 7% tested developing a salivary gland infection, compared to 42% and 24% of Ae. aegypti and Ae. scutellaris, respectively. These results suggest that Ae. scutellaris may have been responsible for DENV transmission on Torres Strait islands, where Ae. aegypti does not occur. In contrast, Ae. albopictus may not be an important vector of DENV-2 from the Torres Strait.

摘要

为确定它们在澳大利亚北部托雷斯海峡地区登革病毒（DENV）传播中的相对作用，我们检测了登革病毒2型（DENV-2）的一个同域毒株在白纹伊蚊、埃及伊蚊和斯氏伊蚊中的感染与传播情况。在使用膜饲器进行病毒暴露的实验中，斯氏伊蚊和埃及伊蚊的感染率分别为83%和43%。两种蚊子的唾液腺感染率均为43%。在使用棉球进行病毒暴露的实验中，埃及伊蚊、斯氏伊蚊和白纹伊蚊的感染率分别为68%、55%和37%。白纹伊蚊表现出最大的感染障碍，只有7%的受试个体出现唾液腺感染，相比之下，埃及伊蚊和斯氏伊蚊的这一比例分别为42%和24%。这些结果表明，在托雷斯海峡群岛上，斯氏伊蚊可能负责登革病毒的传播，因为那里没有埃及伊蚊。相比之下，白纹伊蚊可能不是托雷斯海峡地区DENV-2的重要传播媒介。