31476例巴西单胎妊娠胎儿生物测量参数参考图表。

Reference charts of fetal biometric parameters in 31,476 Brazilian singleton pregnancies.

作者信息

Araujo Júnior Edward, Martins Santana Eduardo Félix, Martins Wellington P, Júnior Julio Elito, Ruano Rodrigo, Pires Claudio Rodrigues, Filho Sebastião Marques Zanforlin

机构信息

Referral Center for Teaching of Diagnostic Imaging, São Paulo, Brazil (E.A.J., C.R., S.M.Z.F.); Department of Obstetrics, Paulista School of Medicine, São Paulo Federal University, São Paulo, Brazil (E.A.J., E.F.M.S., J.E.J.); Department of Obstetrics and Gynecology, School of Medicine of Ribeirão Preto, São Paulo University, Ribeirão Preto, Brazil (W.P.M.); Ultrasonography and Retraining Medical School of Ribeirão Preto, Ribeirão Preto, Brazil (W.P.M.); and Department of Gynecology and Obstetrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas USA (R.R.).

出版信息

J Ultrasound Med. 2014 Jul;33(7):1185-91. doi: 10.7863/ultra.33.7.1185.

DOI:10.7863/ultra.33.7.1185

PMID:24958405

Abstract

OBJECTIVES

The purpose of this study was to establish reference charts of fetal biometric parameters measured by 2-dimensional sonography in a large Brazilian population.

METHODS

A cross-sectional retrospective study was conducted including 31,476 low-risk singleton pregnancies between 18 and 38 weeks' gestation. The following fetal parameters were measured: biparietal diameter, head circumference, abdominal circumference, femur length, and estimated fetal weight. To assess the correlation between the fetal biometric parameters and gestational age, polynomial regression models were created, with adjustments made by the determination coefficient (R(2)).

RESULTS

The means ± SDs of the biparietal diameter, head circumference, abdominal circumference, femur length, and estimated fetal weight measurements at 18 and 38 weeks were 4.2 ± 2.34 and 9.1 ± 4.0 cm, 15.3 ± 7.56 and 32.3 ± 11.75 cm, 13.3 ± 10.42 and 33.4 ± 20.06 cm, 2.8 ± 2.17 and 7.2 ± 3.58 cm, and 256.34 ± 34.03 and 3169.55 ± 416.93 g, respectively. Strong correlations were observed between all fetal biometric parameters and gestational age, best represented by second-degree equations, with R(2) values of 0.95, 0.96, 0.95, 0.95, and 0.95 for biparietal diameter, head circumference, abdominal circumference, femur length, and estimated fetal weight.

CONCLUSIONS

Fetal biometric parameters were determined for a large Brazilian population, and they may serve as reference values in cases with a high risk of intrauterine growth disorders.

摘要

目的

本研究旨在为巴西大量人群建立二维超声测量胎儿生物测量参数的参考图表。

方法

进行了一项横断面回顾性研究，纳入了31476例妊娠18至38周的低风险单胎妊娠。测量了以下胎儿参数：双顶径、头围、腹围、股骨长度和估计胎儿体重。为评估胎儿生物测量参数与孕周之间的相关性，创建了多项式回归模型，并通过决定系数（R²）进行调整。

结果

18周和38周时双顶径、头围、腹围、股骨长度和估计胎儿体重测量值的均值±标准差分别为4.2±2.34和9.1±4.0厘米、15.3±7.56和32.3±11.75厘米、13.3±10.42和33.4±20.06厘米、2.8±2.17和7.2±3.58厘米、256.34±34.03和3169.55±416.93克。所有胎儿生物测量参数与孕周之间均观察到强相关性，以二次方程最佳表示，双顶径、头围、腹围、股骨长度和估计胎儿体重的R²值分别为0.95,0.96,0.95,0.95和0.95。