IEEE Trans Med Imaging. 1986;5(4):229-32. doi: 10.1109/TMI.1986.4307781.
An echo-time encoding NMR chemical shift imaging proposed by Dixon is generalized to be applicable to multiline chemical shift imaging. The method utilizes the phase differences among nuclei encoded by shifting the position of the rf pulse in the spin echo sequence to resolve chemical shift images. The inevitable phase error caused by the static field inhomogeneity is corrected by using phase images of phantom images measured under the same conditions as the actual measurements. The minimum number of encodings can be reduced to half the number of chemical shifts without sacrificing spatial resolution. The experiments were carried out for 3-line 1H chemical shifts using benzene, water, and acetone at 0.5 T. All the chemical shift images could be clearly resolved with only two scans when the field inhomogeneity was larger than the maximum chemical shift difference.
狄克逊提出的回波时间编码 NMR 化学位移成象法已推广应用于多谱线化学位移成象。该方法利用在自旋回波序列中移动射频脉冲位置对核进行相位编码,以分辨化学位移图象。用在与实际测量相同条件下测量的模拟图象的相位图象来校正由静态磁场不均匀性引起的不可避免的相位误差。在不牺牲空间分辨率的情况下,编码数可减少到化学位移数的一半。在 0.5T 下用苯、水和丙酮进行了 3 线 1H 化学位移的实验。当磁场不均匀性大于最大化学位移差时,只用两次扫描就能清晰地分辨出所有的化学位移图象。