Garcia R, Ugarte G, Vidotto V
Departamento de Dermatologia, Universidad Nacional San Antonio Abad, Cusco, Peru.
Mycoses. 1991 Nov-Dec;34(11-12):493-7. doi: 10.1111/j.1439-0507.1991.tb00866.x.
Three cases of paracoccidioidomycosis observed in 1990-1991 in Quillabamba, Peru, and its surroundings are described. The climate and the living conditions of the inhabitants favour paracoccidioidomycosis. It can be assumed that a majority of cases could not be identified, because the symptoms are disguised as other tropical diseases. The application of ketoconazole to the patients showed different results, from optimal to scarce, while temporary remission of the disease was obtained with itraconazole. The best therapy for paracoccidioidomycosis appears to be the application of amphotericin B plus sulphamidics.
本文描述了1990年至1991年在秘鲁基拉班巴及其周边地区观察到的三例副球孢子菌病病例。当地的气候和居民的生活条件有利于副球孢子菌病的发生。可以推测，大多数病例可能未被识别，因为其症状被伪装成了其他热带疾病。给患者使用酮康唑后效果各异，从最佳到不佳，而使用伊曲康唑可使疾病暂时缓解。治疗副球孢子菌病的最佳疗法似乎是两性霉素B加磺胺类药物联合应用。
