Marques S A, Dillon N L, Franco M F, Habermann M C, Lastoria J C, Stolf H O, Marcondes J, Grizzo W, Silva N C, Cavariani M R
Mycopathologia. 1985 Jan;89(1):19-23. doi: 10.1007/BF00437128.
A comparative study of two groups of patients with paracoccidioidomycosis was carried out with the objective of comparing the evolutionary serologic, clinical and radiologic results after 6, 12, 15 and 18 months of treatment with ketoconazole (22 patients) or amphotericin B plus sulfonamides (32 patients). The serologic data analyzed as a whole showed a tendency to sharper drops in antibody titers in the patients treated with ketoconazole. Clinically patients treated with ketoconazole fared better but the differences were not statistically significant. No statistical difference was detected between groups in terms of the results of radiologic evolution.
对两组副球孢子菌病患者进行了一项对比研究，目的是比较酮康唑治疗组（22例患者）和两性霉素B加磺胺类药物治疗组（32例患者）在治疗6、12、15和18个月后的血清学、临床及影像学演变结果。整体分析的血清学数据显示，酮康唑治疗的患者抗体滴度有更明显下降的趋势。临床方面，酮康唑治疗的患者情况较好，但差异无统计学意义。两组在影像学演变结果方面未检测到统计学差异。
