Almaslmani M, Derbala M F, Albozom I, Khattab M, Chacko K, Alani A
Department of Medicine, Infectious Disease, Doha, State of Qatar.
Transpl Infect Dis. 2008 Oct;10(5):339-42. doi: 10.1111/j.1399-3062.2008.00300.x. Epub 2008 Feb 3.
We report a patient who presented 6 months after orthotopic liver transplantation (OLT) with fever, dyspnea, and pulmonary infiltrates with biopsy-confirmed Pneumocystis jiroveci infection associated with a process of bronchiolitis obliterans organizing pneumonia (BOOP). We present this second case of BOOP associated with P. carinii pneumonia after OLT to highlight the risk of such disease combination in all transplant patients as well as discuss the protective effect of post-transplant prednisolone with trimethoprim-sulfamethoxazole prophylaxis and the possible duration of prophylaxis.
我们报告了一名原位肝移植（OLT）术后6个月出现发热、呼吸困难和肺部浸润的患者，经活检证实为耶氏肺孢子菌感染，并伴有闭塞性细支气管炎机化性肺炎（BOOP）。我们呈现这例OLT术后与卡氏肺孢子虫肺炎相关的BOOP的第二例病例，以强调所有移植患者中这种疾病组合的风险，并讨论移植后泼尼松龙联合甲氧苄啶-磺胺甲恶唑预防的保护作用以及可能的预防持续时间。
