Kodati Rakesh, Tadepalli Anuradha, Reddy Chandana, Chakravarthi Rajasekhara, Kumthekar Girish, Tagore Ravindranath
Department of Pulmonary Medicine, Star Hospitals, Hyderabad, Telangana, India.
Department of Nephrology, Star Hospitals, Hyderabad, Telangana, India.
Lung India. 2020 Sep-Oct;37(5):441-444. doi: 10.4103/lungindia.lungindia_487_19.
Organizing pneumonia (OP), previously known as bronchiolitis obliterans OP, is a diffuse parenchymal lung disease affecting the distal bronchioles, alveolar ducts, and alveolar walls. Pulmonary infections, especially bacterial and viral diseases, are known to be associated with the secondary form of OP. OP secondary to fungal infections is less common. Here, we report a case of OP associated with pneumocystis pneumonia (PCP) in a kidney transplant recipient on tacrolimus-based triple immunosuppression. The index case had developed new lung consolidation toward the end of trimethoprim-sulfamethoxazole therapy for PCP. Spontaneous clinical and radiographic resolution was seen without any increment in the dose of corticosteroids. We review the literature and present a summary of all reported cases of OP associated with PCP to date.
机化性肺炎（OP），以前称为闭塞性细支气管炎机化性肺炎，是一种累及远端细支气管、肺泡管和肺泡壁的弥漫性肺实质疾病。已知肺部感染，尤其是细菌和病毒疾病，与继发性OP有关。继发于真菌感染的OP较少见。在此，我们报告一例在接受基于他克莫司的三联免疫抑制治疗的肾移植受者中发生的与肺孢子菌肺炎（PCP）相关的OP病例。该索引病例在接受甲氧苄啶-磺胺甲恶唑治疗PCP接近尾声时出现了新的肺部实变。在未增加皮质类固醇剂量的情况下，临床和影像学表现自发缓解。我们回顾了文献，并总结了迄今为止所有报道的与PCP相关的OP病例。
