Harrison Brooke C, Leinwand Leslie A
Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, CO 80309, USA.
Cell Metab. 2008 Feb;7(2):97-8. doi: 10.1016/j.cmet.2008.01.003.
Akt1 is a well-characterized mediator of muscle hypertrophy. In this issue of Cell Metabolism, Izumiya et al. (2008) reveal a striking link between Akt1 signaling, fast muscle fiber size, and whole-body metabolism. These results provide new insights into the ability of muscle to combat diet-induced obesity and metabolic dysfunction.
Akt1是一种已被充分表征的肌肉肥大介质。在本期《细胞代谢》中，泉谷等人（2008年）揭示了Akt1信号传导、快肌纤维大小与全身代谢之间的显著联系。这些结果为肌肉对抗饮食诱导的肥胖和代谢功能障碍的能力提供了新的见解。
