用肌肉对抗脂肪：增加肌肉量以达到减肥目的。
Fighting fat with muscle: bulking up to slim down.
作者信息
Harrison Brooke C, Leinwand Leslie A
机构信息
Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, CO 80309, USA.
出版信息
Cell Metab. 2008 Feb;7(2):97-8. doi: 10.1016/j.cmet.2008.01.003.
PMID:18249167
Abstract
Akt1 is a well-characterized mediator of muscle hypertrophy. In this issue of Cell Metabolism, Izumiya et al. (2008) reveal a striking link between Akt1 signaling, fast muscle fiber size, and whole-body metabolism. These results provide new insights into the ability of muscle to combat diet-induced obesity and metabolic dysfunction.
摘要
Akt1是一种已被充分表征的肌肉肥大介质。在本期《细胞代谢》中，泉谷等人（2008年）揭示了Akt1信号传导、快肌纤维大小与全身代谢之间的显著联系。这些结果为肌肉对抗饮食诱导的肥胖和代谢功能障碍的能力提供了新的见解。
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