Pan Y, Birngruber R, Engelhardt R
Appl Opt. 1997 May 1;36(13):2979-83. doi: 10.1364/ao.36.002979.
The fundamental difference between time-resolved and coherence-gated imaging modalities in scattering media is analyzed in terms of their optical transfer functions. The effectiveness of coherence gating for multiple-scattering rejection is shown by imaging a 100-mum-thick razor blade hidden in the scattering phantoms (i.e., Intralipid suspensions) with different scattering coefficients. We found that the imaging contrast is limited by multiple scattering and speckle effects in high-scattering media, and the measured effective penetration depth of optical coherence tomography is approximately equal to six mean free paths under the experimental conditions of a numerical aperture of less than 0.1 and a scattering anisotropy of approximately 0.8.
从光学传递函数的角度分析了散射介质中时间分辨成像和相干选通成像模式之间的根本区别。通过对隐藏在具有不同散射系数的散射体模（即脂微球悬浮液）中的100微米厚剃须刀片进行成像，展示了相干选通在多重散射抑制方面的有效性。我们发现，在高散射介质中，成像对比度受多重散射和散斑效应的限制，并且在数值孔径小于0.1且散射各向异性约为0.8的实验条件下，光学相干断层扫描测量的有效穿透深度约等于六个平均自由程。
